CLEARANCE Flashcards

1
Q

LOWEST CLEARANCE

A
  • GLUCOSE
  • ZERO because normally glucose does not appear in the urine
  • decrease reabsorption clearance
  • Na above ZERO
  • urea
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2
Q

largest volume that a kidney can clear

A
  • 600 ml/min

(120 ml/min PAH by filtration and 480 ml/min by secretion)

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3
Q

clearance of INULIN is the volume filtered

A
  • 120 ml/min = GFR

- SLIGHT increase secretion clearance of CREATININE

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4
Q

ALDOSTERONE INCREASES

A
  • reabsorption of SODIUM

- DECREASING THE CLEARED VOLUME

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5
Q

PTH

A
  • increases calcium reabsorption
  • decreases the volume cleared
  • increase clearance of PO4
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6
Q

dehydrated individual

A
  • clearance of UREA IS DECREASED
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7
Q

diuresis

concept UREA always follows WATER

A
  • clearance of UREA IS INCREASED
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8
Q

when is GLUCOSE HAS A POSITIVE CLEARANCE

A
  • as soon as it appears in the urine
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9
Q

CREATININE VALUE

A
  • is always slight increase in GFR (120ml/min)
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10
Q

free water clearance is measured

A
  • by the balance between solute and water excretion
  • is used to determine whether kidney are responding to maintain normal plasma osmolarity
  • pure water loss in the urine
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11
Q

normal urine osmolarity

A
  • 300 mOsm/L
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12
Q

(+) C h20 hypotonic urine

A
  • osmolarity
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13
Q

(-) C h20 hypertonic urine

A
  • osmolarity > 300 mOsm/L
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