Renal Replacement Therapy - Transplantation Flashcards
1
Q
Where is a transplanted kidney placed in the body?
A
Iliac fossa
2
Q
What is the criteria for receiving a donor who died from brain death?
A
Body temperature above 34C Coma, unresponsive to stimuli Absence of cephalic reflexes Absence of drug intoxication Apnoea off ventilator despite build up of CO2
3
Q
What are the complications after transplant?
A
Rejection (cell mediated, humoral)
Cardiovascular ( hypertension, hyperlipidaemia, post transplant diabetes)
Infective (bacterial, viral, fungal)
Malignancy (skin, lymphoma, solid cancers)
4
Q
What drugs are used as immunosuppression after transplant?
A
Predisolone Azathioprine Cyclosporin Tacrolimus MMF
5
Q
What are the primary effects of cytomegalovirus?
A
CMV syndrome Gastroenteritis Nephritis Hepatitis Pneumonitis Retinitis
6
Q
What are the risk factors for BK virus?
A
Intensity of immunosuppression
Patients determinants
Organ determinants
Viral determinants
7
Q
What is the treatment for BK virus?
A
Modification of immunosuppression
Antiviral therapy
