[renal manifestations of systemic} Flashcards
1
Q
A
DM
2
Q
A
4
3
Q
A
elevated GFR
glomerular hyperfiltration
microalbuminaemia
nephropathy
4
Q
A
glomerular/tubular hypertrophy
renal blood flow increase
5
Q
A
Advanced glycosylation end products AGE (glycosylated proteins) trigger destructive disease
deposition of type 4 collagen
mesangial expansion
arterial/GBm thickening/sclerosi
hyperfiltration therefore no microalbuminaemia
6
Q
A
Yes
7
Q
A
5-10 years
8
Q
A
5-10 years (microalbuminaemia)
9
Q
A
reduced GFR
10
Q
A
AGE induced sclerotic lesions
11
Q
A
j