[renal manifestations of systemic} Flashcards

1
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DM

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2
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4

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3
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elevated GFR
glomerular hyperfiltration
microalbuminaemia
nephropathy

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4
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glomerular/tubular hypertrophy

renal blood flow increase

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5
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Advanced glycosylation end products AGE (glycosylated proteins) trigger destructive disease
deposition of type 4 collagen
mesangial expansion
arterial/GBm thickening/sclerosi
hyperfiltration therefore no microalbuminaemia

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6
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Yes

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7
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5-10 years

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8
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5-10 years (microalbuminaemia)

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9
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reduced GFR

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10
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AGE induced sclerotic lesions

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11
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j

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