[nephrotoxins+rhabdo] Flashcards
1
Q
A
acute tubular necrosis
interstitial nephritis
2
Q
A
NSAIDs
3
Q
A
Hb
4
Q
A
myoglobin
5
Q
A
light chains / Igs
6
Q
A
crystals
7
Q
A
radiocontrast material
8
Q
A
phenytoin
lamotrigine
valproate
9
Q
A
Aminoglycosides penicillins sulfonamides rifampicin amphotericin
10
Q
A
gentamicin
amikacin
streptomycin
11
Q
A
give single bolus cf. extended regimens
12
Q
A
pre-hydrate with 0.9% sodium chloride
13
Q
A
urate
K+
CK
PO4 3-
14
Q
A
AKI
Hyperkalaemia
15
Q
A
muscle pain
muscle swelling
red/brown urine
16
Q
A
serum CK (>1000iu/L)
17
Q
A
+ haematuria
BUT WITHOUT BLOOD ON MICROSCOPY
18
Q
A
no RBCs
Blood on dipstick
19
Q
A
MI
20
Q
A
rule out MI
21
Q
A
troponin
22
Q
A
reduced
23
Q
A
enters muscle
24
Q
A
Hyperkalaemia Tx \+ IV Fluid rehydration to prevent AKI \+ Sodium bicarbonate
25
Q
A
alkalise the urine. Myoglobin to less toxic form.
26
Q
A
T
27
Q
A
DIC
