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Renal > Renal histology > Flashcards

Renal histology Flashcards

1
Q

Endothelial cell

A

Lines blood vessels, regulates exchange

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2
Q

Basement membrane

A

ECM, provides support between epithelial tissues

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3
Q

Podocyte

A

Bowman’s capsule, wraps around glomerulus

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4
Q

Primary pedicle

A

Processes from podocytes - trabecular

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5
Q

Secondary pedicle

A

Branching from primary pedicles

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6
Q

Filtration slits

A

Spaces between pedicles on glomerular basement membrane

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7
Q

Malpighian corpuscle

A

Beginning of nephron, glomerulus and Bowman’s capsule

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8
Q

Mesangial cells

A

Form mesangium of glomerulus and renal corpuscle

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9
Q

Bowman’s space

A

Between visceral and parietal layers

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10
Q

Bowman’s capsule

A

Beginning of nephron, filters blood initially

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11
Q

PCT

A

Reabsorbs glucose

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12
Q

DCT

A

Acid-base balance, fine tunes concentrations

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13
Q

Glomerular capsule

A

Bowman’s capsule

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14
Q

Macula densa

A

Lines DCT where it meets with LOH

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15
Q

Juxtaglomerular cells

A

Secrete renin

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16
Q

Vascular pole

A

Arterioles enter and leave glomerulus

17
Q

Urinary pole

A

PCT, outflow of glomerular filtrate

18
Q

Arterioles

A

Afferent brings blood to and efferent away

19
Q

Glomerulus

A

Network of blood vessels at beginning of nephron

20
Q

Renal corpuscle

A

Blood filtering component of nephron

21
Q

Collecting tubules

A

Transport urine from nephrons to larger ducts and CD

22
Q

LOH

A

Conducts urine, recovery of water and NaCl

23
Q

What happens when BP falls?

A
  • Kidneys sense decrease in BP and release renin from JGA
  • Renin converts angiotensinogen to angiotensin i
  • ACE (angiotensin-converting enzyme) converts angiotensin i to angiotensin ii
  • Angiotensin ii = vasoconstriction = increased BP
  • Angiotensin ii stimulates aldosterone release from adrenal glands
  • Aldosterone promotes reabsorption of sodium and water
  • BP and volume increases
24
Q

What does PCT do?

A

Absorb 80% of ions

25
Q

What does descending LOH do?

A

Water escapes here

26
Q

What does ascending LOH do?

A

Release NaCl

27
Q

Where is ADH released from?

A

Posterior pituitary

28
Q

Action of aldosterone on DCT

A

Retains sodium but not potassium or hydrogen

29
Q

Where is aldosterone released

A

Zona glomerulosa

30
Q

How do cells from the PCT appear under a microscope?

A

Single layer of large cuboidal cells, brush borders small, uneven lumen, dark pink staining

31
Q

How do cells from the DCT appear under a microscope?

A

Single layer of medium cuboidal cells, smaller perimeter than PCT, larger lumen than PCT

32
Q

How do cells from the LOH appear under a microscope

A

Simple squamous cells

33
Q

How do cells from the CD appear under a microscope?

A

Simple cuboidal cells, most pale staining cells, very distinct basement membrane

Renal (26 decks)

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