Renal Clearance and Transport Flashcards
What is whole body clearance?
Total rate of removal of a substance by all organs
What is renal clearance?
The virtual volume of blood plasma needed to supply the amount of solute that appears in the urine; the amount of plasma that is completely cleared of a solute per unit time
Formula for urinary excretion rate:
(Ux)(V)
Ux= urine concentration
V= rate of urine formation
What is urinary excretion rate?
Amount of x excreted in the urine/time
GFR formula:
GFR= (Ux x V)/Px
How are urea and glucose both filtered?
Freely filtered
What is PAH typically used as a measure for?
Renal plasma flow
What is Inulin a measure of?
Glomerular filtration rate (glomerular marker)
What is the clearance ratio formula?
Cx/Cinulin
Formula for renal blood flow:
RPF/(1-hematocrit)
Formula for renal plasma flow:
[U]pah x V/[P]pah