Antibiotics I Flashcards

1
Q

What are 3rd generation cephalosporins used to treat?

A

Some gram + more so gram - cocci

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2
Q

Aminoglycosides:

A

Streptomycin

Kanamycin

Neomycin

Gentamicin

Amikacin

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3
Q

What are the two general categories of DNA topoisomerases?

A

Quinolones

Fluoroquinolones

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4
Q

Miscellaneous cell wall inhibitors:

A

Bacitracin

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5
Q

What are 2nd generation cephalosporins used to treat?

A

Gram + cocci and some gram -

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6
Q

Tetracyclines:

A

Doxycycline

Minocycline

Tetracycline

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7
Q

What are penicillin 1st generation drugs?

A

Benzyl penicillin (oral) Penicillin V (oral)

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8
Q

Two categories of 50s ribosomal subunit binders:

A

Macrolides

Chloramphenicol

Lincosides

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9
Q

What are the narrow spectrum penicillinase-resistant penicillins?

A

Dicloxacillin Oxacillin Nafcillin Methicillin

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10
Q

What are the 4th generation cephalosporins?

A

Cephepine

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11
Q

What are broad-spectrum penicillinase sensitive drugs?

A

Ampicillin Amoxicillin Pipericillin

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12
Q

Two categories of 30s ribosomal subunit inhibitors:

A

Aminoglycosides (bacteriocidal)

Tetracyclines (bacteriostatic)

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13
Q

Chloramphenicol:

A

Chloramphenicol

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14
Q

What are the two general bacterial protein synthesis inhibitors?

A

30s ribosomal subunit inhibitors 50s ribosomal subunit inhibitors

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15
Q

Macrolides:

A

Azithromycin

Clindamycin

Erythromycin

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16
Q

What are 4th generation cephalosporins used to treat?

A

Gram + cocci and gram - cocci

17
Q

What are the two general categories of anti-folate drugs?

A

Sulfanamides

Dihydrofolate reductase inhibitors

18
Q

Three types of penicillins?

A

Narrow spectrum - penicillinase-sensitive Narrow spectrum - penicillinase-resistant Broad spectrum - penicillinase-sensitive

19
Q

How do penicillins work?

A

Covalently bond and inactivate penicillin bind protein (peptidase forming a cross link in the cells wall)

20
Q

What are the 2nd generation cephalosporins?

A

Cefoxitin

21
Q

What are the 3rd generation cephalosporins?

A

Cefteriaxone

22
Q

Carbapenem antibiotic

A

Imipenem

23
Q

Glycopeptide antibiotic:

A

Vancomycin

24
Q

Fluoroquinolones:

A

Ciprofloxacin

Levofloxacin

25
Q

What are non-beta-lactam cell wall inhibitors?

A

Miscellaneous cell wall inhibitors Glycopeptide antibiotics

26
Q

What are 1st generation cephalosporins used to treat?

A

Gram + cocci

27
Q

What are the beta-lactam (cell wall synthesis inhibitors) antibiotics?

A

Penicillins Cephalosporins Carbapenems Monobactams

28
Q

What are the 1st generation cephalosporins?

A

Cephazolin

Cephalexin

29
Q

Lincosides:

A

Clindamycin

30
Q

Monobactam antibiotic:

A

Aztreonam

31
Q

DHFR inhibitors:

A

TMP

Pirymethamine