Renal Clase 2 Flashcards

1
Q

Gasto Cardiaco de Riñones

A

Cuarta Parte

22-25%

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2
Q

Division Arterial Renal

A
  1. Arterias Renales
    - Anteriores y Posteriores (Segmentarias)
    - Superior e Inferior (Segmentarias)
  2. Arteiras Interlobulares
  3. Arterias Arcuatas
    - interlobulillares
    EN CORTICALES
  4. Capilares peritubulares
    EN YUXTAGLOMERULARES
  5. Vasos rectos
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3
Q

RBF (Renal Blood Flow)

A

Volumen de sangre entregada a pulmones por unidad de tiempo… recibe 22%… por ende RBF= 1.1 L/MIN en un hombre de 70Kg

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4
Q

RPF (Renal Plasma Flow)

A

Volumen de plasma entregado a riñones por unidad de tiempo… 1.1L/MIN el 55% es plasma… RPF= 625mL/MIN

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5
Q

Effective Renal Plasma Flow

A

RPF(0.9)

Because only 90% of plasma in blood reaches the nephrons

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6
Q

Glomerular Filtration Rate

A

Volume offload filtered by all corpuscles of both kidneys per minute (180L Daily)
GFR= 180L/24h* (1000ml/1L)* (1Hour/60min)
125 ml/min MALES

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7
Q

Filtration Fraction

A

1140ml/min es delivered al riñón
55% es plasma (625ml/min)
solo del 16 al 20% es filtrado (125ml/min)

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8
Q

Que pasa con FF en personas de tercera edad

A

Se reduce a 10%

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9
Q

Principal característica de arterial AFERENTE

y su presión

A

Cual arterial es la principal encargada de flujo sanguíneo y filtración glomerular
Presión de 60mmgh

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10
Q

Vasoconstirctores

A

EPI
NOREPI
Angiotensina II
Endotelina
Todas estimuladas por un bajo fluido extracellular
Disminuyen Glomerular Filtration Rate y Renal blood flow

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11
Q

Vasodilatadores

A

Prostaglandinas (Cuando baja LEC o aumenta Angiotensina II)
Oxido Nitrico (NO)
Bradikinin (Prostaglandinas bajas)
Natriurietic Peptides (cuando sube LEC)
Todas causan un aumento en Glomerular filtration rate y Renal blood blow

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12
Q

Net filtration pressure

A

Pressure needed for filtrate formation

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13
Q

NFP Formula

A

Glomerular hydrostatic pressure- oncotic pressure of glomerular blood- capsular hydrostatic pressure

GBHP-BCOP-CHP= NFP
55- 30- 15= 10

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14
Q

Presiones Importantes

A

Aferente 55-60mmgh
Presión hidrostática en E. Bawman 15mmgh (Pb)
Presión oncotica proteínas 30mmgh (Mas filtración = mas presión de proteínas)(PiG)

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15
Q

Factors that can decrease Glomerular Filtration Rate

A

Baja de Kf
Subida de Pb o PiG

Diabetes Mellitus, Hypertension, Renal Disease
Less Renal Blood Flow, arterial pressure, angiotensin II

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16
Q

Aclaramiento renal Formula

A

Clearance of solute X= (Amount of Solute X excreted/Concentration of solute X in plasma)
POR MINUTO

17
Q

Que pasa con la glucosa

A

Toda es reabsorbida

18
Q

Que es usado para estimar el renal plasma flow

A

PAH Paraaminohippuric acid

EstimateRenalPlasmaFlow = Clearance PAH

19
Q

Ejemplo de sustancia que es excretada al 100%

A

INULINA

20
Q

Diferencias entre Reabsorcion, Secreción y Clearance o filtración

A

SOLO FILTRACION (GFR=C in)
FILTRACION Y REABSORCION PARCIAL (Csub < C in)
FILTRACION Y COMPLETA REABSORCIÓN
FILTRACIÓN Y COMPLETA SECRECIÓN (Csub > C in)

21
Q

Creación de Creatinina

A

Creatina
Phospocreatinina
Creatinina (Depende muscle mass)

22
Q

Relación entre creatinina y GFR

A
Inversamente proporcional 
10% urinary C from tubular excretion
10% serum C chromogens
VALUES CANCEL EACH OTHER
C Clearaance higher whenGFR falls over 60ml/min
...
23
Q

Donde actúan VC y VD

A

VC arteriola eferente

VD arterial aferente