Renal Cancer: Wilms Tumor Flashcards
1
Q
renal cancer
A
two groups:
- Wilms tumor
- renal cell carcinoma
2
Q
wilms tumor
A
- composed of embryogenic tissue/fetal tissue
- mostly in 1 kidney
- 2-5 yr
- associated w/ congenital abn (ex. aniridia)
- associated w/ Chr abn (eg. WT1 on Chr 11)
- single mass that’s palpable
3
Q
what are the 3 components of a malignancy?
A
stromal, epithelial tissue, and blastoma
4
Q
what does WT1 code for?
A
factor involved with normal kidney development
5
Q
staging
A
look at the location, r/t how they can deal with it surgically
stage 1: w/in kidney, NOT affecting the capsule
stage 2: malignancy extends into capsule
stage 3: malignancy extends into the abdomen
stage 4: lung mets
6
Q
complications
A
HTN and edema d/t fluid retention
7
Q
diagnosis
A
- CT
- detected after mass is present
8
Q
treatment
A
- Sx and chemo
- prognosis is good if picked up early -> 95% long-term survival rate
