Renal Body Fluid Compartments -Rogers Flashcards
total fluids ingested in a day
2100 total intake = 2300
volume contraction
ECF volume is decreased = decreased blood volume, lowered BP
volume expansion
ECF volume increases
Hyperosmotic
osmolarity in the ECF increased
amount of water in the body
50% - 70%
amount in ICF and ECF
ICF : 2/3 ECF : 1/3
ECF is what
interstital fluid (around cells) plasma (in blood vessels) * divided by capillary wall
ICF is what
intracellular fluid only inside cells
water is added where and leaves from the body from where
leaves and enters the body from the ECF
controlling the plasma does what to the interstitual fluid
controls the intestitiual fluid the same way
non-electrolyte electrolyte
nonelectrolyte : cant dissolve in water (lipids, glucose, urea) and have no charge electrolytes : dissolve in water and have charge ****can change fluid volumes more****
ICF composition
K+, PO4-3, anion proteins
ECF composition
NA+, Cl-, HCO-3, some anion proteins (ONLY in plasma) no proteins in interstitual fluid
hypotonic cell environment does what
swells the cell
Na+ concentration in ECF
140mEq
N + concentration ICF
5mEg
3 main solutes in the ECF
sodium Glucose Urea (BUN)
Serum osmolality calculation
Osmolality = (NA+ x 2) + (glucose)/18 + (BUN)/2.8
Serum osmolality calculation eyeball it
plasma osmolality = 2 (plasma NA+)
when is ADH secreted from PP
andiotensin 2 low preload high plasma osmolality sympathetic activation =Increase BP (H2O and some NA reabsorption)
ANP has what 3 functions
- Arterial dilation (decrease TPR) 2. increase fluid loss (decrease preload_ 3. inhibit renin, aldosterone, ADH (decreases TPR and preload)
sweating and lots of fluid loss does what
water moves out from ICF to the ECF and cells shrink
sweating a lot and drinking equally as much water as lost
increase water in ECF and no NA+ increased (hyposmolarity) = cells swell
2 types of dehydration
- Hypernatremic dehydration 2. Hyponatremic dehydration
Hyponatremic dehydration
more NA+ loss then water loss water moves TO ICF ECF is hypoosmolality - tachycardia, hypotention
Hypernatremia dehydration
more H2O loss then NA water moves TO ECF ECF is hyperosmolality * can cause edema
Hypernatremia dehydration and Hyponatremic dehydration can cause what symptoms
confusion brain cells shrink or swell weakness, muscle cramps hyperreflex
Darrow-Yannet Diagrams during volume contraction casues and what happens
hyperosmotic enviornment Diabetes, dehydration, alcoholism, De ECF, De ICF, In osmolality
Darrow-Yannet Diagrams during diabetes casues and what happens
excessive thirst and urination 1. body cant make ADH, or kidneys cant respond to ADH= volume contraction = water keeps getting excreted 2. increased glucose pulls water into CD
Water diuresis
increased H2O excretion (no NA) caused from diabetes*, increased water intake
solute diuresis
increased H2O and NA+ excretion caused by high NACL in diet hyperglycemia* high protein intake AKI recovery
Darrow-Yannet Diagrams during adrenal insufficiancy casues and what happens
no aldosterone can be made In ICF, De ECF, De osmolality
Darrow-Yannet Diagrams during SIADH (inappropriate ADH) + excess water intake casues and what happens
ECF is hypotonic In ECF, In ICF, De osmolality
Darrow-Yannet Diagrams during hemorrage, diarrhea, vomiting casues and what happens
only ECF loss SAME ICF and SAME osmolality
Darrow-Yannet Diagrams during injecting isotonic NACL saline casues and what happens
ECF INCREASES ICF + osmolality = same
Darrow-Yannet Diagrams during very high NACL intake and saline injection casues and what happens
ECF increases INF decreases, osmolality decreases (water goes from ICF to ECF) from ingesting NA+
when does hematocrit increase
when ECF decreases (when ECF increases, Hematocrit decreases since you have added to it)
Look at these 2 tables
Look at these 2 tables****
