Pulmonary Physiology Topics - Dr. Rogers Flashcards

1
Q

inspiration P and V

A

V increases when P decreases by 1mmGH (when chest cavity opens)

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2
Q

Interpleural P

A

less then atmospheric P, (from -5 to -8)

-8 during end of inspiration

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3
Q

Alveolar P

A

= atmospheric pressure (0) at rest
during inspiration when chest cavity opens = decreases to -1
CAUSES AIR TO COME IN

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4
Q

Transpulmonary P

A

Palv - Ppl

at rest Ptp = 0 - (-5) = 5

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5
Q

alveolar P at the end of inspiration (most air inside)

alveolar P at the beginning of inspiration

A

0 for both

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6
Q

alveolar P in the middle of inspiration

alveolar P in the middle of expiration

A

-1

+1

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7
Q

Ppl at the end of inspiration

Ppl at the beginning of inspiration

A
  • 8

- 5

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8
Q

Ppl at the middle of inspiration

Ppl in the middle of expiration

A

-6.8 for both

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9
Q

air flow rate is the same as
air flow rate at the middle of expiration
air flow middle of inspiration

A

Alveolar P
+1
-1

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10
Q

air flow rate at the beginning of inspiration

air flow rate at the end of inspiration

A

0

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11
Q

Lung compliance and chest wall graph is what

A

the average of both lung compliance wanting to collapse and the chest wall wanting to spring outward
X : P getting more negative
Y : V getting more positive

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12
Q

FRC Lung compliance and chest wall graph

A

equilibrium V between lung and chest wall

= when chest wall is at 35% capacity and lung capacity is at 45%

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13
Q

Minute Ventilation

A
how much air someone is getting every min
*NORMAL = 7000ml/min = 7L/min*
= Tidal Volume x f
f is RR
500ml/br x 14br/min = 7L/min
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14
Q
EMPHYSEMA
RV
TLC
FVC
FEV1
FEV1/FVC
peak expiratory flow rate
A
*obstructive 
increased
increased
decreased
decreased
decreased
decreased
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15
Q
FIBROSIS
RV
TLC
FVC
FEV1
FEV1/FVC
peak expiratory flow rate
A
Restricted
decreased
decreased
decreased some
same
same
decreased
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16
Q

dead space in emphysema

dead space is fibrosis

A

larger

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17
Q

finding anatomical dead space

A

1ml per lb of body weight

mine is 118mL of anatomical dead space

18
Q

alveolar DS

A

air in alveolus that is inside only doesn’t get blood

19
Q

Minute Alveolar Ventilation (Valv and V(dot)alv)

A
amount of air that participates in gas exchange per min
Valv= TV-DS
= 550mL - 250mL = 300mL
V(dot)alv = Valv x f
= 300mL x 11br/min = 3.3L/min
20
Q

EMPYSEMA
compliance
elastic recoil

21
Q

FIBROSIS
compliance
elastic recoil

22
Q

chest wall and lung compliance graph is what kind of graph

A

sigmoid so that the middle part is the ideal range
small P change (negative P around lungs) leads to large volume change (volume in the lungs)
* COMPLIANCE = SLOP of line at the point on sigmoid graph

23
Q

at low lung volume

A

larger P change needs to happen to increase V of air into lungs (hard to stretch lungs)

24
Q

at volume around TLC

A

larger P needed to increase V of air into lungs

hard to stretch lungs

25
inflating lungs with saline fluid causes what
increases compliance
26
Hysteresis
the difference in inspiration (needing more P) and expiration (diffusive) this happens due to LaPlace's Law
27
LaPlace's Law
Surfactant reducing ST in the smallest alveoli more then the larger ones
28
P to inflate lungs is fibrosis and in emphysema
fibrosis : more P | Emphysema : less P
29
Fibrosis and obesity | compliance, RR, volume inhaled
lower, higher RR, lower V inhaled
30
age and compliance
increases
31
Emphysema and FRC
FRC shifts up the graph | equilibrium of chest wall and lungs are at an increased volume (lung needs less P)
32
Fibrosis and FRC
FRC shifts downwards | equilibrium is at a lower volume (lung needs more P)
33
Bronchodilator does what
B2 adrenergic, blocking parasympathetic
34
air in the alveoli in emphysema
it doesn't get access to blood for gas exchange
35
what happens as a side effect of
interdependence = alveoli hold each other open against the lung wanting to collapse
36
Elastic Forces during inspiration and expiration
work to overcome during breathing from elastic forces (to keep lungs uncollapsed)
37
Loop on the graph
work to overcome for breathing from resistive forces (in inhale the air) inhale needs p exhale reduces P due to diffusion
38
Work of breathing in restrictive
fibrosis change in elastic work needed = increases overall work *more negative Ppl needed to inhale air in
39
Work of breathing in obstructive
emphysema change in resistive work both during inhalation and exhalation = increase overall work *higher Ppl needed to exhale air out of lung
40
change in elastic work (increased) on RR
higher HR
41
change in resistive work in airflow (increased) on RR
lower HR