renal Flashcards
glomerulonephritis
inflammatory reaction in glomerulus
- antibodies lodge = scarring, bad filtering
- main cause: strep
acute can lead to chronic
main cause of glomerulonephritis
strep
s/s of renal failure
retain toxin: malaise headache anorexia nausea, vomiting
retain H2O:
decreased uop
weight gain
nephrotic syndrome
inflammatory response in the glomerulus = big holes = proteinuria = hypoalbuminemia = fluid out of vascular space into tissue = hypovolemia = kidneys try RAAS = anasarca
PS
- hyperlipidemia because liver trying to compensate by making more albumin which releases cholesterol, triglyercides
- blood clots (missing protein factors to prevent)
anasarca
total body edema
nephrotic syndrome tx
diuretics
- water out
ACE-I
- stop aldosterone
prednisone
- decrease inflammation (holes)
anti-lipemics
anti-coagulation therapy up to 6 months
dialysis
pre-renal failure
blood can’t get to kidneys
think shock, hypotension
intra-renal failure
damage has occurred within kidney
think dyes, drugs, glomerulonephritis, nephrotic syndrome, DM, htn
post-renal failure
urine can’t get out of kidneys
think enlarged prostate, kidney stone, tumors, edematous ileal conduit stoma
renal failure electrolyte imbalances x3
hyperkalemia (think: lethal arrhythmias) metabolic acidosis (can't filter out H+) retained phosphorus --> serum Ca down --> Ca out of bones
oliguric phase of renal failure
decreased uop (100 - 400mL/24 hours) fluid volume excess, hyperkalemia
diuretic phase of renal failure
sudden onset; increased uop
fluid volume deficit (shock!), hypokalemia
thrill
palpate - cat purr sensation
bruit
auscultate turbulent flow