Renal Flashcards

1
Q

Spikes and Dome

Subepithelial deposit

A

Membranous GN

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2
Q

Tram track

A

Membranoproliferative GN

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3
Q

N GFR

A

125

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4
Q

Wire loop

A

Lupus nephritis

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5
Q

Double countour

A

Membranoproliferative GN

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6
Q

Rash + renal problem

A

Henoch schonlein purpura

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7
Q

Renal blood flow in both kidneys

A

1100 ml/min

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8
Q

Flank pain
Painless hematuria
Palpable mass
Smoker

A

Renal Cell Ca

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9
Q

Massive proteinuria

A

3g/dl

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10
Q

Massive proteinuria
Hypoalbuminemia
Edema
Hyperlipidemia

A

Nephrotic syndrome

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11
Q

Problem with Distal tubule

A

Nephrogenic Diabetes Insipidus

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12
Q

Microalbuminuria

A

30-299 mg/dl

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13
Q

Macroalbuminuria

A

> 300mg/dl

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14
Q

Pathognomonic for Minimal Change disease

A

Foot process effacement

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15
Q

Post renal transplant rejection

A

Malignant nephrosclerosis

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16
Q

Bacteria in PSGN

A

Group A beta hemolytic strep (strep pyogenes)

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17
Q

Hyalinosis

Epithelial damage

A

Focal Segmental Glomerulosclerosis

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18
Q

Proteinuria in Membranous GN

A

MAC (C5b-C9)

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19
Q

Prototypical exogenous IC pattern

A

PSGN

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20
Q

2 major histologic condition in progressive glomerular disease

A

Focal segmental Glomerulosclerosis

Tubulointerstitial damage

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21
Q

Ischemic nephropathy

A

Aminoglycoside
Amphothericin B
Contrast agent

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22
Q

Bilaterally enlarged kidneys
Multiple cyst
Pain, hematuria

A

Adult Polycystic Kidney disease

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23
Q

Analgesic nephropathy increases risk for

A

Transitional Papillary Ca of the Renal Pelvis

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24
Q

Most common site of abdominal aneurysm

A

Infrarenal

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25
Drug for post op urinary bladder atony
Bethanecol
26
Most common GN worldwide
IgA nephropathy
27
Drugs that can cause Membranous GN
Penicillamine | Captopril
28
Hypersensitivity reaction in Good Pasteur
Type II
29
Reduction in GFR that would progress to ESRD
30-50%
30
ADH control
Distal tubule and collecting duct
31
Bladder filling
Sympathetic
32
Most common gene mutation in APKD
PKD1
33
Capillary wall damage
Membranous GN
34
Associated with Proteus infection
Stag horn calculi
35
Marked sense of bladder fullness
400-500ml
36
Associated with HIV and heroin
Focal Segmental Glomerulosclerosis
37
Ca associated with Schistosoma Hematobium
Squamous cell bladder Ca
38
Female Reproductive age Proteinuria, rbc cast HTN
Lupus nephritis
39
Pulmonary alveolar hemorrhage Anti-GBM Linear IG deposits
Type 1 RPGN - Good Pasteur
40
End artery occlusion
White infarct | Wedge shape
41
Most common NS in children
Minimal Change Disease/Lipoid Nephrosis
42
Most common NS in adult
Membranous GN
43
Prototypical endogenous IC pattern
SLE
44
Lumpy bumpy
Post strep GN
45
Enlarged, hypercellular glomeruli | Mesangial and monocytes interposition
Membranoprliferative GN
46
Gene causing cyst formation
Polycystin 1
47
Cyst formation
Abnormal cellular matrix Fluid secretion Cell proliferation
48
Foot process effacement
Minimal change disease
49
Lipid laden PCT
Minimal change disease
50
Diagnostic work up for DM nephropathy
24 hr urine protein
51
6 y/o throat pain, fever | 1-2weeks after, hematuria, proteinuria, periorbital edema
Post strep GN
52
APKD associated with
Liver cyst | Berry aneurysm
53
Nerve deafness
Alport syndrome
54
Alport syndrome
Type IV collagen
55
Times plasma volume filtered
60
56
Renal Ca treatment
Nephrectomy
57
Congenital disorder by ACEI
Renal agenesis
58
Most common Lupus nephritis
Diffuse Proliferative Glomerulonephritis
59
Bladder emptying
Parasympathetic
60
Urge to void
150ml
61
BP control for DM and HTN
ACEI and ARB
62
Countercurrent multiplier
Loop of Henle
63
Impermeable to urea
Thick ascending limb DCT Cortical collecting duct
64
Treatment for PSGN
Penicillin | Macrolide
65
Most common Renal Ca
Clear cell
66
Transport of sugar and amino acid
Secondary active transport
67
Most common Renal Ca in children
Nephroblastoma/Wilm's tumor
68
Drug causing Interstitial nephrosclerosis
Methicillin | Analgesic
69
Edema Foamy urine Unintentional weight gain Anorexia
DM nephropathy
70
Major sodium reabsorption
PCT
71
Countercurrent exchange
Vasa recta
72
Highly permeable to water
Thin descending limb
73
No sodium transport
Thin descending limb
74
Dictates water permeability
Aquaporin
75
Normal blood pH
7.4
76
Poor response to steroids
Membranous GN
77
Good response to steroids
Minimal change disease RPGN Lupus nephritis
78
Aspirin, Phenacetin, NSAID
Analgesic nephropathy
79
Analgesic nephropathy
Aspirin, Phenacetin, NSAID
80
Hallmark of Focal segmental Glomerulosclerosis
Epithelial damage
81
Most abundant CHON excreted in urine
Tamhorsfall protein
82
Water reabsorption
PCT
83
WAGR Syndrome
Wilm's tumor Aniridia Genitourinary problems Retardation
84
Highest vascular resistance in kidneys
Interlobar Afferent arteriole Efferent arteriole
85
Regulation of urine concentration
Medullary countercurrent system | ADH
86
Secrete ADH
Supraoptic nuclei in post pituitary
87
Kimmelsteil - Wilson lesion
DM nephropathy
88
Nodular Glomerulosclerosis
DM nephropathy
89
% water reabsorbed
99%
90
Sclerosis of arteries | Long standing HTN
Benign nephrosclerosis
91
Leather grain appearance
Benign nephrosclerosis
92
Na transport
Primary active
93
Glucose transport
GLUT 2/SGLT
94
Amount of protein in urine
Zero
95
Drug that cause Diabetes Insipidus
Lithium
96
Lithium
Diabetes Insipidus
97
Urea reabsorption
PCT
98
ANCA positive | Systemic Vasculitis
Type III RPGN
99
Secrete renin
JG cells
100
Amount of fluid filtered per day
180L
101
Impermeable to water
Thick ascending limb
102
Most common type of lupus
Type IV - Diffuse Proliferative Glomerulonephritis
103
Regulate GFR
Filtering membrane Particle size, shape and charge Filtering forces Blood flow
104
Abdominal bruit
Renal artery stenosis | Abdominal aneurysm
105
Most potent stimulus for erythropoietin production
Hypoxia
106
Kidney function
Excretion Homeostasis Endocrine
107
HTN Abdominal bruit Dyslipidemia
Renal artery stenosis
108
Maintains bladder tone
Detrusor muscle
109
Weight of kidneys
150mg
110
Treatment for acute exacerbation of lupus nephritis
Steroids
111
Basic functional unit of kidney
Nephron
112
% phenol reabsorbed
Zero
113
Embryologic origin of collecting duct
Ureteric bud
114
Hormones secreted by kidney
Erythropoietin Prostaglandin Renin Vit D
115
Primitive urine
Glomerular filtration
116
Embryologic origin of nephron
Metanephric blastema
117
Avascular part of kidney
Medulla
118
Leading cause of ESRD
DM nephropathy
119
Na sensor
Macula densa
120
Placement of donor kidney
Iliac fossa
121
Basic renal process
Glomerular filtration Tubular reabsorption Tubular secretion
122
Onion skinning
Malignant nephrosclerosis
123
Fibrinoid necrosis
Malignant nephrosclerosis
124
% CO that kidney receives
25%
125
Accelerated rise in BP
Malignant nephrosclerosis
126
Systemic diseases causing NS
SLE Amyloidosis DM
127
Problem with post pituitary
Central diabetes Insipidus