Renal Flashcards
Rhabdomyolysis Lab results
Metabolic acidosis
hyperK+
hypoCa2+: myoglobin binds to calcium
hyperPOC3: released from myocyte
high CK level : x5 time upper limit of normal
Rhabdomyolysis mx
ivi
urinary alkalinisation sometimes used
nephrotic syndrome TRIAD
proteinuria 1g/m2 per 24 hrs, hypoalbuminaemia <25g/L, oedema
commonest nephrotic syndrome in children
Minimal change disease
What does hypokalaemia predispose
Digoxin toxicity
Max infusion rate hypokalaemia
Rate of infusion should not exceed 2pm of/hr
CKD stages
- > 90ml/min eg for with some signs of kidney damage on other tests
- 60-90ml/min with some signs of kidney disease
3a. 45-59ml.min mod reduction
3b. 30-44ml/min - 15-29.
- < 15ml/min established kidney failure
CKD HTN and other mx
Diet: low protein, phosphate, sodium, potassium diet
HTN: ACE inhibitor helpful. Acceptable decrease in egfr 25% and increase Cr 30%. Furosemide other anti-HTN
Increased risk of IHD
DCM can occur due to hyperuraecaemia
Absolute criteria of AKI
Increase in creatinine >25umol/l in 48hrs
>50% rise in creatinine over 7d or
Decrease in UO <0.5ml/kg/hr for >6hours or
>25% fall in eGfR in children/ young adults in 7 days