Immunology

Question 1

Anaphylaxis mx

Answer 1

adrenaline im

Question 2

refractory anaphylaxis mx

Answer 2

refractory after 2 doses of adrenaline

consider iv adrenaline infusion

Question 3

adrenaline dose for anaphylaxis

Answer 3

adrenaline 1:1000
<6months- 0.15mg (ml)
6-6yrs- 0.15mg
6-12yrs 0.3mg
>12yr 0.5mg

Question 4

location of im adrenaline for anaphylaxis

Answer 4

anterolat aspect of MIDDLE third of thigh

Question 5

anti mitochondrial ab ass disease

Answer 5

PBC

Question 6

anti-Jo1 Ab

Answer 6

idiopathic inflammatory myopathies esp polymyositis + dermatomyositis.

Question 7

What to check after anaphylactic reaction

Answer 7

Tryptase level

Question 8

Risk stratification anaphylaxis

Answer 8

Fast track d/c: after 2 hrs sx resolution, good response to single dose of adrenaline

Min to hours: x2 doses of adrenaline needed/ prev biphasic reaction

Min 12 hrs: >2 doses needed, severe asthma, possibility of ongoing reaction, late onset at night