Dermatology Flashcards

1
Q

Koebner phenomenon + disease associated

A

trauma precipitate new lesion

Vilitigo
Lichen Planus

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2
Q

Mx vilitigo

A

sunblock
topical corticosteroid-> may reverse if given early

tacrolimus + phototx

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3
Q

Lichen Planus characteristic

A

P’s

Purple
Pruritic
Papular
Poylgonal

White lace pattern on buccal mucosa

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4
Q

Lichen Planus mx

A

potent topical steroid

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5
Q

Psoriasis classification + which most common type

A

Plaque- most common
Flexural
Guttate
Pustular

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6
Q

Auspitz’s sign

A

Seen in psoriasis: when scale removed, red membrane w/ pinpoint bleeding may be seen

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7
Q

What is Guttate psorasis ass with?
Mx psoriasis guttate: resolved spontaneously 2-3month

A

transient psoratic rash freq (+ streptococcal infection 2-4wks prior to lesion appearing

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8
Q

Psoriasis Mx

A

1st line: potent corticosteroid + vit D analogue (topical bethamethasone + topical calcipotriol) OD

2nd line: no improvement after 8 wks-> vit D analogue BD

3rd line: no improvmenet after 8-12wks corticosteroid BD for 4 weeks. coal tar pre OD/BD

SECONDARY CARE:
phototx: PUVA
systemic tx: po MTX/ ciclosporin/ systemic retinoids/ biologics/ ustekinumab

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9
Q

acanthosis nigrans

A

Gastric cancer

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10
Q

tylosis

A

oesophageal cancer

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11
Q

Tinea Capitis mx

A

Trichophyton po terbinafine
microsporum infection: griseofulvin

topical ketoconazole shampoo given 2 weeks decreases transmission

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12
Q

Tinea corporis mx

A

po fluconazole

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13
Q

Herald patch

A

seen pityriasis rosea. recent resp tract infection 1-2 weeks later by multiple erythematous, slightly raised oval lesion with fine scale confined to outer aspects of the lesion.

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14
Q

Pityriasis rosea mx and pathogen

A

self limiting

HHV7 may play a role

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15
Q

Pityriasis Versicolour- pathogen + mx

A

Tinea Versicolor. Malassezia Furfur.

Topical antifungal. ketoconazole shampoo.

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16
Q

Impetigo causative pathogen

A

Staph aureus/ strep pyogenesI

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17
Q

Impetigo Sx + Mx + school exclusion criteria

A

golden crust, hydrogen peroxide 1% cream, fusidic cream unless resistance suspected mupirocin

Extensive: po fluclox, erythromicin if pen allergic

@ home until lesion crusted + healed OR 48hrs after starting abx

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18
Q

Dermatitis Herpetiformis what disease ass, Dx, Mx

A

ass w/ coeliac disease. Cause by deposition of IgA.

skin biopsy: direct immunofluorescance deposition of IgA in granular patter in upper dermis

Ab-TTG

Mx: gluten free diet, Dapsone

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19
Q

sebaceous cyst mx

A

surgical excision

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20
Q

Acquired ichthyosis skin condition

A

Lymphoma

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21
Q

Skin condition seen in oesophageal cancer

22
Q

Causes of erythema nodosum

A

Infection: streptococcus, TB, brucellosis
Systemic: sarcoidosis, IBD Behects
Malignancy/ lymphoma
Drugs: penicillins, sulphonamides, COCP
Pregnancy

23
Q

Live do reticularis causes

A

Idiopathic most common
P0lyarteritis nodosum
SLE
Cryoglobulinaemia
APS
eDS
Haemocystinuria

24
Q

Chronic plaque psoriasis mx

A

1st line: corticosteroid applied, vit D analogue

Secondary care: photo tx- UV-B light with psoralen (PUVA)

Po MTX 1st line esp useful if ass. Joint disease, ciclosporin

25
Mx psoriasis guttate
Most cases resolve spontaneously within 2-3 months, same as plaque psoriasis
26
Mx of venous ulcer
Compression bandaging Po pentoxifylline- periph vasodilator can improve healing
27
Pathogen causing molluscum contagious and mx
Mollucscum contangiosum virus member of poxvirida3 Mx: usually self-limiting, avoid sharing towels, clothing . Squeezing with finger nail, crypto
28
Causes of seborrhoeic dermatitis and associated disease
Inflammatory reaction related to prolif of normal, skin Malassezia Furfur HIV, PD
29
Mx of seborrhoeic dermatitis
Ketoconzaole 2% shampoo 1st line Topical steroid- face and body
30
Eczema herpeticum pathogen and mx
Severe primary infection of HsV1 or 2 Mx: life threatening !!! Iv aciclovir
31
Impetigo mx
Causes by staph aureus, strep pyogenes Mx mupirocin topical or Rushdie acid if resistant suspected If systemically unwell/ high risk complication- hydrogen peroxide 1% cream Extensive po fluclox, erythromycin if pen-allergic
32
Which scoring system used for hirsutism
Ferryman-Galway scoring system
33
Which hypersensitivity in contact dermatitis
Type IV delayed hypersensitivity
34
Toxic epidermal necrolysis which sign
Nikolsky signs: epidermis separates with mild lat pressure
35
Oemphigus vulgaris pathogenesis
Autoimmune disease- Ab against desmoglein 3 Flaccid blister, oral mucosa
36
Bullous pemphigoid pathogenesis
Autoimmune condition causing sub-epidermal blistering of skin Tense blister, no mucosal involvement , flexor surface Skin biopsy : immunofluorescence IgG+ C3 at dermoepidermal junction
37
Pemphigus vulgaris vs bullous pemphigoid
Vulgaris: intraepidermal Ab against dermoglein 3, flaccid and [sinful blister, oral mucosa common Pemphigoid Subepidermal, tense and itchy blister, flexor surfaces
38
Guttate psoriasis vs pityriasis rosea
Guttate: streptococcal sore throat 204 weeks, tear drop Pityriasis rosea: recent Resp tract infection, herald patch
39
Erythema multiforme causes
Hypersensitivity reaction usually triggered by infection Viruses: HSV idiopathic, bacteria: mycoplasma, streptococcus, Drugs: penicillin, sulphonamides, carbamezepine, allopurinol, NSAIDS, COCP, Connective tissues disease, sarcoidosis, malignancy
40
Steven’s Johnson syndrome causes
Severe systemic reaction affects skin & mucosa Penicillin, sulphonamides, lamotrigine, carbamazepine, phenytoin, allopurinol, NSAIDS, COCP
41
Surge Weber syndrome what skin condition and mx
Port wine stain unilateral. Ipsilateral leptomeningesl angioma, diffuse choroidak haemangioma, glaucoma, seizure, focal neurological deficit Mx: cosmetic, laser tx- multiple session needed
42
Actinic keratoses mx
Fluorouracil crea 2-3 weeks- skin will become red and inflamed
43
Squamous carcinoma of skin mx
Surgical excision 4mm margin if lesion<20mif >20mm margins 6mm
44
Which skin cancer is most common
Basal cell carcinoma
45
Rosacea what is it and mx
Chronic skin condition unknown aetiology, aggregated by hot and spicy food Mx: topical bromid gel, brimonidin alpha AG, Mild-mod papules with/out pustules: topical ivermectin Mod-severe: topical ivermectin + po doxycycline
46
Rosacea vs seborrhoeic dermatitis
Rosacea: cerrofaciak, rhinophyma Seborrhoeic: scale and scalp and preauricular
47
Mild -mod acne vulgaris mx
12 week course of topical combo Topical adapalene with topical benzoyl peroxide Fixed combo topical tretinoic with topical clindamycin
48
Mod-severe acne vulgaris mx
12 week course of Fixed combo topical adapalene + topical benzoyl peroxide Fixed combo topical tretinoin + topical clindamycin Fixed combo topical adapalene with or without po lymecycline or po doxycycline
49
Fungal nail infection mx
If dermatophyte/ candidate: limited involvement- topical [amorolfine 5% nail lacquer More extensive dermatoohyte: po terbinafine More extensive candida: po itraconazole
50
Scabies mx
Alive close contact All household and close contacts should be treated at the same time Permethrin 5% 1st line Malathion 0.5% 2nd line
51
What is actinic keratoses
Aka solar keratoses Premalignant skin lesion- small crusty, scaly lesions- pink/red/brown sun exposed areas