Renal Flashcards
What is the most common organism causing UTIs?
E. coli
What 3 agents can be used to tx pyelo?
Ciprofloxacin, levofloxacin or ceftriaxone
What happens to serum Cr in kidney risk?
Increased x 1.5
What happens to serum Cr in kidney injury?
Increased x 2
What happens to serum Cr in kidney failure?
Increased x 3
What is kidney loss defined as?
Complete loss of kidney function > 4 weeks
What is end-stage kidney disease defined as?
Complete loss of kidney function > 3 months
What happens to GFR in kidney risk?
Decreased by 25%
What happens to GFR in kidney injury?
Decreased by 50%
What happens to GFR in kidney failure?
Decreased by 75%
What is the most common cause of nephrotoxicity?
Nephrotoxic agents
What class of drugs is most commonly nephrotoxic? What is their suffix?
Aminoglycosides (drugs ending in -micin)
Acute tubular necrosis is what type of kidney injury?
Intrarenal
What is the fractional excretion of sodium in prerenal kidney injury?
<1
What is urine sodium in prerenal kidney injury?
> 20 mmol/dl
What is urine specific gravity in prerenal kidney injury?
> 1.015
What is serum BUN to Cr ratio in prerenal kidney injury?
> 10:1
What three drugs are standardly given for kidney stones?
Morphine or hydromorphone, toradol, metoclopramide
What does metoclopramide have a black box warning for?
Extrapyramidal side effects
PSA value greater than what is abnormal?
4
Can you have prostate CA with a normal PSA?
Yes
What class of drug is standard of care for BPH?
Alpha blockers
What herbal med can be used to reduce sx in BPH?
Saw palmetto
What three classes of meds can make BPH sx worse?
Antihistamines, decongestants and SSRIs
What is normal Cr clearance in men?
97 to 137 ml/min
What is normal Cr clearance in women?
88 to 128 ml/min