Hematology Flashcards

1
Q

What is normal Hgb in women?

A

12-16

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2
Q

What is normal Hgb in men?

A

14-18

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3
Q

What is normal Hct in women?

A

37-47%

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4
Q

What is normal Hct in men?

A

40-54%

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5
Q

What is normal TIBC?

A

250-450

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6
Q

What is normal serum iron?

A

50-150

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7
Q

What is normal MCV?

A

80-100

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8
Q

Microcytic anemia is most commonly caused by what?

A

Iron deficiency anemia or thalassemia

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9
Q

Macrocytic anemia is most commonly caused by what?

A

B12 or folate deficiency, alcoholism, liver failure

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10
Q

Anemia of chronic disease causes what type of anemia?

A

Normocytic

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11
Q

Sickle cell disease causes what type of anemia?

A

Normocytic

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12
Q

What type of anemia is iron deficiency anemia?

A

Microcytic, hypochromic anemia

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13
Q

What is the leading cause of iron deficiency anemia?

A

Blood loss

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14
Q

Which anemia is characterized by having a high red cell distribution width?

A

Iron deficiency anemia

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15
Q

Low serum ferritin and high TIBC point to what?

A

Iron deficiency anemia

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16
Q

When should iron be given in relation to food?

A

1-2 hours after meals

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17
Q

Taking iron with juices high in what can increase absorption?

A

Vitamin C

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18
Q

What type of anemia is thalassemia?

A

Microcytic, hypochromic

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19
Q

What ethnicity is most likely to have thalassemia?

A

Asian

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20
Q

Are people with thalassemia minor heterozygous or homozygous for beta thalassemia?

A

Heterozygous

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21
Q

Which type of thalassemia is more common in adults?

A

Thalassemia minor

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22
Q

Which type of anemia is characterized by decreased alpha or beta hemoglobin chains?

A

Thalassemia

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23
Q

Folic acid deficiency is what type of anemia?

A

Macrocytic, normochromic anemia

24
Q

Glossitis is typical of what types of anemia?

A

Folic acid and B12 deficiency

25
How to differentiate folic acid deficiency anemia from B12 deficiency anemia?
No neuro signs are seen with folic acid deficiency
26
How to treat folic acid deficiency?
Folic acid 1mg/day
27
What type of anemia is pernicious anemia?
Macrocytic, normochromic anemia
28
Cyanocobalamin is also known as what?
B12
29
Which anemia is most common in alcoholism?
Folic acid deficiency
30
Vitamin B1 is also known as what?
Thiamine
31
What type of anemia is anemia of chronic disease?
Normocytic and normochromic
32
How is anemia of chronic disease managed?
By treating the associated disease
33
How do you manage sickle cell crisis?
Fluids, pain meds and O2
34
What is Von Willebrand disease?
Genetic disorder resulting in reduced ability to create blood clots
35
Which clotting factor is affected in Von Willebrand?
Factor VIII
36
How is Von Willebrand disease managed?
With desmopressin
37
Most leukemia in adults is what type?
Chronic lymphocytic anemia
38
What is the hallmark of acute lymphocytic leukemia?
Pancytopenia with circulation blasts
39
What is the hallmark of chronic lymphocytic anemia?
Lymphocytosis
40
What is the hallmark of chronic myelogenous leukemia?
Philadelphia chromosome
41
How is a diagnosis of leukemia confirmed?
Bone marrow aspiration
42
How is leukemia managed?
Chemo and bone marrow transplantation
43
Incidence of tumor lysis syndrome can be reduced with which drug?
Allopurinol
44
What is the difference between stage II and stage III lymphoma?
Stage II involves lymph nodes on one side of the diaphragm; stage III involves lymph nodes on both sides of the diaphragm
45
What type of cells differentiate Hodgkin's lymphoma from non-Hodgkin's?
Reed-Sternberg cells (occur in Hodgkin's)
46
Is radiation used for leukemia or lymphoma?
Lymphoma
47
What is a normal platelet value?
150,000-400,000
48
What is the platelet count in DIC?
Less than 150,000
49
What is fibrinogen in DIC?
Less than 170 mg/dl
50
What is FDPs (fibrin degradation products) in DIC?
Greater than 45
51
What is PT in DIC?
Greater than 19 seconds
52
What is PTT in DIC?
Greater than 42 seconds
53
What three things to give for DIC?
Platelet transfusions, FFP, and cryoprecipitate
54
What else must be given if RBCs are being transfused in large amounts?
FFP
55
What does cryoprecipitate do in DIC?
Maintains fibrinogen levels
56
What does FFP do?
Replaces clotting factors