Regulation Of The Heart Rate Flashcards

1
Q

Which part of the heart contracts first?

A

Atrium

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2
Q

How is the heart a dual pump?

A

The left and right sides of the heart pump blood separately, but simultaneously, into the systemic and pulmonary circuits.

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3
Q

Cardiac contraction is triggered by…

A

…depolarization of CM that arises from the SAN

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4
Q

What is the normal heart rate

A

60 to 80 bpm

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5
Q

When is bradycardia physiologically normal?

A
  • At sleep

- In trained athletes

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6
Q

When is tachycardia physiologically normal?

A
  • In children
  • Excitement
  • Exercise
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7
Q

Agents that mimic PNS and SNS

A

PNS - Propanolol

SNS - Atropine

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8
Q

Agents that’s going to mimic the action or effects of the SN are referred to as

A

Catecholamines

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9
Q

What is the Intrinsic HR?

A

Seen when after the blockage of sympathetic and parasympathetic NS. It is 100bts/min

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10
Q

Factors responsible for heart rate regulation

A

BBHNCRV

Baroreceptor
Bainbridge reflex
Higher Centres
Neural
Chemoreceptor
Respiration
Ventricular Receptor
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11
Q

What controls the CVN?

A

Medulla oblongata

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12
Q

Steps in PNS neural regulation

A
  1. CVN cells controlled by medulla synapse with postganglionic on epicardium surface near SAN and AVN
  2. Right goes to SAN, left to AVN
  3. Effect = Reduction
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13
Q

The effect of the SNS In increasing the heart rate is a gradual process. True or false?

A

True

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14
Q

Does the hypothalamus increase or reduce heart rate?

A

It leads to an alteration in the heart rate, depending on which part of it is stimulated

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15
Q

What are the higher centers of the brain?

A

Frontal lobe of the brain
The cerebral cortex
The thalamus
Hypothalamus

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16
Q

The baroreceptors are located in…

A

…the Aortic Arch and Carotid sinuses

17
Q

How do the baroreceptors cause changes in the heart rate?

A

They elicit changes in the heart rates due to acute changes in arterial blood pressure

18
Q

What is the relationship between the arterial blood pressure and heart rate?

A

They are inversely proportional to one another

19
Q

How does the Bainbridge reflex work?

A

Increase in blood volume or infusion of saline evokes the Bainbridge reflex, increasing the HR, magnitude of which depends on the prevailing HR.

20
Q

What else is evoked by the Bainbridge reflex?

A

The baroreflex which antagonizes its action.

21
Q

The actual change in HR depends on…

A

…the antagonistic effects of the baroreceptor reflex

22
Q

Effect of Bainbridge reflex on heart rate?

A

Increases HR. Will be low if blood volume is increased and baroreflex is greater then Bainbridge

23
Q

Atrial receptors are found in…

A

…the right atria wall

24
Q

What is dysrythmia?

A

An alteration in the rhythm of the heartbeat

25
How does respiration affect the heart rate?
The heart rate is increased during inspiration and reduced during expiration
26
What causes change of heart rates during respiration?
Changes in neural activity during the respiratory cycle
27
Stimulation of arterial chemoreceptors has a dual effect on the heart rate. True or false?
True
28
What determines the effects of arterial chemoreceptors on the heart rate?
The site of stimulation
29
The primary reflex effect of stimulation of arterial chemoreceptors is to...
...facilitate the medullary vagal centre and thereby to decrease HR
30
The secondary effects of the stimulation of arterial chemoreceptors are to...
...inhibit the medullary vagal centre and cause pulmonary hyperventilation
31
There are ventricular receptors in the wall of the ventricles that can have strong effects on the heart rate. True or false?
False. They have mild effects.
32
What does excitation of the endocardial receptors in the ventricles do?
It diminishes HR and peripheral resistance