Regulation Of Arterial Blood Pressure Flashcards

1
Q

What are the two pathways for ABP regulation?

A
Local regulation (one part)
Global regulation (entire body)
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2
Q

Local control of ABP involves…

A

Regulation of ABP to an organ by local control or constriction of a vessel

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3
Q

Agents responsible for local regulations are

A

Those responsible for vasoconstriction and vasodilation

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4
Q

Agents responsible for vasoconstriction

A

Angiotensin II
Vasopresine
Cytokines
Oxygen free radicals

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5
Q

Agents responsible for vasodilation

A

Nitric oxide

ANP

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6
Q

Global regulation of ABP is long-term. True or false?

A

True, but not all, just renal

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7
Q

What are the global ABP regulation methods?

A

Nervous
Hormonal
Renal

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8
Q

Nervous control of arterial blood pressure is a long-term way of regulating BP. True or false?

A

False

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9
Q

And what situations does nervous control of ABP kick in?

A

For rapid increase during exercise or stress

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10
Q

Nervous control of arterial blood pressure involves…

A

stimulation of the entire vasoconstrictor and cardioaccelerator functions and inhibition of the parasympathetic vagal inhibitory signals to the CVS

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11
Q

What are the expected changes during nervous control of arterial blood pressure?

A
  • construction of arterioles of systemic circulation to increase the total PR, thereby increasing ABP
  • constriction of veins to increase VR and CO
  • cardioacceleration by SNS
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12
Q

What is the relationship between peripheral resistance and arterial blood pressure?

A

They are directly proportional

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13
Q

The nervous system controls regulation of BP through

A

ANS and reflexes

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14
Q

The nervous system of regulation redistributes blood flow to different areas of the body. True or false?

A

True

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15
Q

What are the different reflexes responsible for short-term regulation of arterial blood pressure by the nervous system?

A

Baroreceptor reflex Chemoreceptor reflex

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16
Q

The components of a reflex

A
Receptor
Afferent neuron
Control center
Efferent neuron
Effector
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17
Q

Afferent pathway for the carotid baroreceptors

A

Hering’s nerves —> Glossopharyngeal nerves in the high neck —>
Tractus solitarius in the medullary area of the brain stem.

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18
Q

The vasomotor center for the baroreceptors is found in

A

Tractus solitarius in the medullary area of the brain stem.

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19
Q

Afferent pathway for the aortic baroreceptors

A

Vagus nerves —> Tractus solitarius in the medullary area of the brain stem

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20
Q

Location of tractus solitarius VMC

A

It is located bilaterally mainly in the reticular substance of the medulla and of the lower third of the pon

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21
Q

The baroreceptor VMC consists of:

A

CAC - Cardioacceleratory center
CIC - …inhibitory…
CEC - …excitatory…

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22
Q

Functions of the VMC

A
  • Decrease HR through vagus nerves and PNS
  • Increase HR through SNS and peripheral sympathetic nerves
  • Produce vasoconstrictor tone
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23
Q

Methods of ABP regulation by baroreceptor reflex

A

Bilateral carotid occlusion

Postural change

24
Q

Which system of arterial blood pressure regulation is called a buffer system?

A

Baroreceptor system

25
Q

In which system of arterial blood pressure regulation are buffer nerves found?

A

Baroreceptor system

26
Q

What is the stimulus for the baroreceptor reflex for arterial blood pressure regulation?

A

Stretch of receptors, increased rate of firing of the normal operating range

27
Q

The organs for the chemoreceptor reflex of arterial blood pressure regulation are…

A
  • Carotid bodies in the bifurcation of the common carotid artery
  • Aortic bodies adjacent to the aorta
28
Q

Stimulus for Chemoreceptor reflex

A

Lack of oxygen
Excess CO2
Hydrogen ion excess

29
Q

Afferents for chemoreceptor reflex

A

Hering’s nerves and the vagus nerves

30
Q

Control centre for chemoreceptor reflex

A

VMC

31
Q

Efferent arm for chemoreceptor reflex

A

ANS

32
Q

Effector organs for chemoreceptor reflex

A

Heart and blood vessels

33
Q

The carotid sinus baroreceptors respond to increase and decrease in arterial blood pressure. True or false?

A

True

34
Q

The aortic arch baroreceptors respond to increase and decrease in arterial blood pressure. True or false?

A

False. They respond to only increase

35
Q

What are the reflexes involved in nervous control about your blood pressure?

A
  • Baroreceptor reflex
  • Chemoreceptor reflex
  • Atrial and pulmonary artery reflexes
  • Atrial Bainbridge reflex
  • Brain (CNS) ischemic response
  • Abdominal contraction reflex
36
Q

Hormonal control of arterial blood pressure acts through

A

RAAS

Renin
Angiotensin
Aldosterone
System

37
Q

Where are epinephrine and norepinephrine produced?

A

The adrenal medulla

38
Q

Where is renin produced?

A

Kidney nephrons

39
Q

Where is aldosterone produced?

A

Adrenal cortex

40
Q

Where is angiotensin produced?

A

Liver

41
Q

Where is ADH or vasopressin produced?

A

Hypothalamus

42
Q

Where is ANP produced?

A

Heart atrium

43
Q

Functions of epinephrine and norepinephrine

A

Temporarily decreases kidney function by vasoconstriction

44
Q

Function of renin

A

Increases blood pressure by acting on angiotensinogen

45
Q

Functions of vasopressin or ADH

A

Promotes water retention

46
Q

Function of ANP

A
  • Decreases BP
  • Decreases sodium reabsorption
  • Increases glomerular filtration rate
47
Q

Will it renin lead to increased blood pressure?

A

Yes, it will

48
Q

Which hormone stimulates production of androtensin?

A

Renin

49
Q

Which hormone is antagonistic to the angiotensin pathway?

A

ANP

50
Q

How does ANP oppose angiotensin?

A

Angiotensin decreases glomerular filtration rate, and increases water retention and blood volume while ANP reduce these.

51
Q

Effect of blood volume and ECF on arterial blood pressure

A

If they are high, arterial blood pressure will be high

52
Q

What is pressure diuresis?

A

The process whereby an increase in body fluid leads to increased blood pressure and increased renal output of water

53
Q

What is pressure natriuresis?

A

The process whereby there is an increase in salt in the body leading to increased blood pressure and increased renal output of salt

54
Q

The renal function curve is a graph of what against what?

A

Urinary volume outputs against arterial blood pressure

55
Q

The equilibrium point on the renal function curve describes…

A

… the level to which the arterial pressure will be regulated.

56
Q

The two primary determinants of the long-term arterial pressure level are as follows…

A
  1. The degree of pressure shift of the renal output curve for water and salt
  2. The level of the water and salt intake line