Regulation of Animal Cell Shape Flashcards

1
Q

What is the cytoskeleton

A

a microscopic network of protein filaments and tubules in the cytoplasm

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2
Q

What are the functions and KEY FEATURES of the cytoskeleton? (4)

A
  • helps maintain cell shape
  • helps maintain position of organelles within cell
  • rapidly disassembles and reassembles
  • highly dynamic but provides stability
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3
Q

What are the 3 main components of the cytoskeleton?

A
  • microtubules
  • microfilaments
  • intermediate filaments
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4
Q

What are the key features and functions of microtubules? (6)

A
  • composed of tubulin subunits
  • may radiate out from an organizing center (centrosome)
  • resist compression
  • maintain cell shape
  • provide cell motility
  • involved with organelle motility
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5
Q

What are the two ways microtubules can provide cell motility?

A
  • flagella ( snake-like motion)

- cilia ( rowing like motion)

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6
Q

How do microtubules aid organelle motility within cell?

A
  • ATP powered motor proteins can “walk” organelles along microtubules
  • they allow vesicles, or other organelles, to be transported to specific targets within cell
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7
Q

What are microfilaments?

A

Double chain of actin subunits

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8
Q

What are the functions and key features of microfilaments? (4)

A
  • form both linear strands and 3 dimensional networks
  • resist tension
  • cortical network under cell membrane make region less fluid and thus maintains cell shape
  • interactions with motor proteins (myosin) support cell movement such as: muscle contraction, amoeboid movement, cytoplasmic streaming in plants
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9
Q

what are the key features of Intermediate Filaments? (5)

A
  • made of various proteins such as: keratins in hair, lamins in nucleus, neurofilaments in neurons
  • supercoiled into cables
  • least dynamic of the cytoskeletal components
  • form relatively permanent cellular structures
  • may remain after cell death
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10
Q

What are the functions of intermediate filaments? (2)

A
  • maintain cell shape

- anchor organelles

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11
Q

What are the 3 major types of cell junctions?

A
  • tight junctions
  • desmosomes
  • gap junctions
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12
Q

What are the key features of tight junctions? (3)

A
  • hold neighbouring cells tightly pressed together
  • may form a continuous seal
  • prevents fluid movement across cell layers
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13
Q

What are the key features of desmosomes? (3)

A
  • anchoring junction
  • provide attachment between sheets of cells
  • connected into the cell by intermediate filaments
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14
Q

What are the key features of gap junctions? (3)

A
  • point of cytoplasmic contact between two cells
  • ions and small molecules can pass between cells
  • allows rapid intercellular communication
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15
Q

what is ECM?

A

non-cellular component present within all tissues and organs

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16
Q

What is ECM composed of? What does each component do? (6)

A
  • Material secreted by cells through exocytosis
  • proteins are glycoproteins ( mostly collagen)
  • collagen fibres are embedded in proteoglycan matrix
  • proteoglycans trap water to resist tension and maintain tissue shape
  • glycoproteins called fibronectins attach cytoskeleton to ECM
  • membrane proteins ( integrins) connect ECM to cytoskeleton