Red Blood Cells - Hematology Flashcards
What are the 3 type of functions?
Transport, regulation and protection
What does blood transport?
Oxygen, CO2, wastes, and hormones
What does blood regulate?
Body temp, maintaining pH and maintaining blood volume
What does blood protect?
Clotting and immune (white blood cells)
What is blood’s characteristics?
Temperature, pH and plasma
What is blood’s temperature?
38 degrees celcius
Blood is composed of __ types of white blood cells
5
What is blood’s pH?
7.35-7.45
Plasma is composed of:
Electrolytes, mostly water, ion, organic molecules, respiratory gases
What is the average amount of blood an adult has?
5-6 L
Plasma is ___% water
90
Which protein is the most abundent?
Albumins
What are the organic molecules you need to know? (also what plasma consists of)
Proteins (albumins), glucose, lipids and amino acids
What does an erythrocyte do?
A red blood cell that carries oxygen from the lungs and deliver it throughout our body
Females have ____ million/mm3 erythrocytes
4.5
Males have ____ million/mm3 erythrocytes
5.5
what does an erythrocyte look like?
Biconcave
What is a hemoglobin?
A protein in red blood cells that carries oxygen from the lungs to the body’s tissues and organs, and carries carbon dioxide back to the lungs
GLobin=
Protein
Hem=
Blood
A red blood cell is ___ um in width
7.5
What does erythropoiesis mean?
Formation of red blood cells
All cells come from:
Hemocytoblasts
A red blood cell is ___ um in height
2.5
One drop of blood = ____ million hemoglobin cells
250
What is the 1st step in the cell process? (committed cell)
Proerythroblast
What is the baby blood cell called?
Reticulocyte
How long is the cell creation process?
15 days
How long is the cell creation process if you’re anemic?
2-5 days
What is erythropoietin?
A hormone secreted by the KIDNEYS that increases the rate of production of red blood cells in response to falling levels of oxygen in the tissues (hypoxia)
What is hypoxia?
Decrease of oxygen in the tissue
What is required for erythropoietin ?
Iron, B vitamins and intrinsic factors
What are the 3 components of blood?
Plasma, buffy coat and erythrocytes
What parts of iron store and transport?
Ferritin and transferrin
How long does a red blood cell last?
120 days
What is bilirubin?
A yellowish pigment that’s produced when the body breaks down old or damaged red blood cells
Where do RBC die?
Spleen
8 blood disorders:
Hemorrhagic, hemolytic, aplastic, nutritional, perniscious, thalassemia, sickle cell and blood doping