Recognition Of Innate Immune Cells

Question 1

What are the general Properties of PRR’s

Answer 1

Specificity= mannose receptors

Receptors=Germ line incoding/limited diversity

Distribution of Receptors= Nonclonial, identical receptors on all cells of same lineage

Discrimination of self and nonself

Question 2

What are the types of Germ line encoded receptors and what does it mean?

Answer 2

Refers to sequences found in gametes

Toll-like receptors

N-formal methionyl receptor/Methionine start codon

Mannose receptor

Question 3

What are PAMP’s

Answer 3

Pathogen-associated molecular patterns

Pattern Recognition Receptors PRR’s

Question 4

What is the role of PRR in Phagocytosis?

Answer 4

Lysosomes and Endosome