Components Of Innate Immunity

Question 1

What are Circulating effector proteins?

Answer 1

Complement

Mannose-binding lectin (Collectin)

C-reactive protein (pentraxin)

Question 2

What does complement do?

Answer 2

Kills microbes

Oposonization

Activate leukocytes

Question 3

What does Mannose-binding lectin do?

Answer 3

Opsonizon ion

Activate lectin pathway

Question 4

What does C-reactive protein do?

Answer 4

Pentraxin

Opsonization

Activate complement

Question 5

What are the cytokines involved in Innate Immunity?

Answer 5

TNF= Inflammation

IL-1= Inflammation

IFN-Alpha, Beta= Viral resistance

IFN-Gamma= Mac activation

IL-12= IFN-gamma production by NK and T-Cells

IL-15= Proliferatrion of NK Cells

IL-10= Control inflammation

TGF-Beta= Control inflammation

Question 6

What are the circulating effector cells?

Answer 6

Neutrophils/early phage

Macrophages/efficient phage, secretion of cytokines for inflammation

NK cells/lysis of infected cells, activate macs