Receptors Flashcards

1
Q

What is the predominate neurotransmitter at the terminal synapse of parasympathetic neurons

A

Ach

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2
Q

M1

A

excitatory- neural (CNS stimulation, gastric acid secretion, increased GI motility)

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3
Q

M3

A

Excitatory-Glandular (secretions, smooth muscle contraction, vasodilation)

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4
Q

M5

A

Excitatory- Salivary glands, iris substantia nigra

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5
Q

M2

A

Inhibitory- Cardiac (cardiac and neural inhibition)

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6
Q

M4

A

Inhibitory- CNS/Smooth muscle

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7
Q

What sympathetic affects of the heart?

A

B-1
Increased HR
Increased Contractility
Increased automaticity and conduction of AV node

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8
Q

What are the Parasympathetics affects of the heart?

A

Decreased HR
- Inotropism
Decreased AV node conduction

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9
Q

What are the neurotransmitters at the terminal synapses of sympathetic neurons?

A

Norepinephrine

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10
Q

What are the Sympathetic affects on the vasculature

A

a-1: vasoconstriction
b-2: vasodilation
a-2: various (vasoconstriction/vasodilation)

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11
Q

What are parasympathetic affects of the Vasculature

A

Vasodilation through release of NO

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12
Q

What are sympathetic affects on the lungs?

A

B-2: bronchodilation, increased resp. secretions

a-2: decrease secretions

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13
Q

What are parasympathetic affects on the lungs?

A

Bronchoconstriction

Increased resp. secretion

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14
Q

What are the sympathetic affects on the GI tracts?

A

a-1,b-1, b-2: decrease motility, close sphincters, inhibit secretion

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15
Q

What are the parasympatheitc affects on the GI tract

A

increase motility
relax sphincters
stimulate secretion

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16
Q

What are sympathetic affects on the bladder?

A

B-2: relaxes detrusser muscle

A-1: contract sphincter

17
Q

What’s the difference between a direct acting and indirect acting drug?

A

Direct- acts directly on the receptor

Indirect- interacts w/ something other than the receptor