Receptors Flashcards
1
Q
How do receptors work
A
2
Q
What is the difference between a substrate and a ligand
A
3
Q
What are the three types of receptors
A
4
Q
How are G proteins activated via the GPCR
A
5
Q
What does the GTP bound alpha subunit do after dissociating from the beta-gamma pair
A
The alpha subunit binds to the intracellular soluble regions of adenylate cyclase
It binds to adenylate cyclase which catalyses the conversion of ATP to cyclic AMP which is then converted to protein kinase A
6
Q
What is the structure of adenylate cyclase
A
7
Q
What does protein kinase A do
A
8
Q
How is the G protein reset
A
9
Q
How is the GPCR deactivated
A
10
Q
Explain the full mechanism for GPCR activation
A