Receptors 1+2

Question 1

what are antacids?
1-4

Answer 1

drugs that don’t bind

Question 2

what are the use of antacids?
1-4

Answer 2

they are neutralising
e.g gaviscon

Question 3

what are diuretics?
1-4

Answer 3

medicines that help reduce fluid build up in the body

Question 4

what is the real definition of an agonist?
1-4

Answer 4

agonist initiate changes in cell function, producing effects of various types

Question 4

what are “blood thinners”?
1-4

Answer 4

anticoagulants

Question 5

what is tachyphylaxis?
1-7

Answer 5

repeating doses/exposure of a drug leads to less response

Question 6

what equation is used to find out the number of receptors being occupied by a drug molecule?
1-12

Answer 6

Hill-Langmuir

Question 7

what does efficacy mean?
1-13

Answer 7

how good a drug doe sits job

Question 9

what is the sign for occupancy?
1-14

Answer 9

PA (A is subscript)

Question 10

when an antagonist is added to a agonist log-concentration-effect curve, what happens to the curve?
1-16

Answer 10

the curve shifts to the right (dextrose shift) (everything else stays the same)

Question 11

things to look for on a graph to show that it is a competitive antagonist
1-18

Answer 11

• dextrose shift (right shift)
• no change in min and max response
• shape of the curve is still the same

Question 12

what does surmountable and insurmountable mean?
1-20

Answer 12

reversible and irreversible

Question 13

what is constitutive activity?
1-24

Answer 13

receptors are active without the sue of agonists

Question 14

what is another name for silent receptors?
2-3

Answer 14

depo sites

Question 15

what are silent receptors?
2-3

Answer 15

receptors that will bind with a drug but does nothing with it