Peptides

Question 1

what differentiates classical peptides to neuropeptides

Answer 1

classical peptides are synthesised with the addition of a precursor,
whereas neuropeptides are part of a larger inactive precursor

Question 2

origin of serotonin

Answer 2

tryptophan

Question 3

origin of dopamine and noradrenaline

Answer 3

tyrosine

Question 4

origin of GABA

Answer 4

glutamate

Question 5

origin of glutamate

Answer 5

glutamine or a-ketoglutarate

Question 6

some examples of neuropeptides

Answer 6

enkephalins
substance p
oxytocin
glucagon
angiotensin

Question 7

name the peptide that regulates appetite

Answer 7

neuropeptide Y (NPY)

Question 8

what is substance P used for

Answer 8

for pain

Question 9

what are factors that can change the cleaving of preproproteins

Answer 9

where in the body they are
where in the brain they in
what co enzyme they expressed with
what type of dense core vesicle they in

Question 10

what enzyme cleave pro glucagon in the gut, pancreas and brain

Answer 10

proconvertase 1-3

Question 11

what neuron does ghrelin activate in the hypothalamus

Answer 11

AgRP neuron

Question 12

what peptide is produced by the POMC neuron

Answer 12

a-MSH

Question 13

when NPY and AgRP is released, what does it do to the Satiety neuron

Answer 13

inactivates the neauron, increasing hunger