RBC Dynamics Flashcards
1
Q
which direction is Fetal Hb shifted
A
left
2
Q
what reduces glutathione in RBC
A
NADPH
3
Q
what is the critical metabolic intermediate of the BPG shunt in erythrocytes
A
1,3 BPG
4
Q
what is the result of 2,3 BPG on oxygen affinity
A
decreases
5
Q
[2, 3 BPG] is managed by what enzyme
A
2,3 BPG mutase
6
Q
EPO is what kind of receptor
A
jak/stat
7
Q
what are the causes of mircocytic, hypochromic RBC
A
HB synthesis
TAILS +B6
8
Q
what are the causes of macrocytic, normachromic RBC?
A
DNA synthesis
B12, FA deficiencies, erythroleukemia
9
Q
what are the causes of normoyctic, hypochromic RBC
A
red cell loss
acute bleeding, sickle cell