RBC Dynamics Flashcards

1
Q

which direction is Fetal Hb shifted

A

left

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2
Q

what reduces glutathione in RBC

A

NADPH

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3
Q

what is the critical metabolic intermediate of the BPG shunt in erythrocytes

A

1,3 BPG

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4
Q

what is the result of 2,3 BPG on oxygen affinity

A

decreases

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5
Q

[2, 3 BPG] is managed by what enzyme

A

2,3 BPG mutase

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6
Q

EPO is what kind of receptor

A

jak/stat

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7
Q

what are the causes of mircocytic, hypochromic RBC

A

HB synthesis

TAILS +B6

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8
Q

what are the causes of macrocytic, normachromic RBC?

A

DNA synthesis

B12, FA deficiencies, erythroleukemia

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9
Q

what are the causes of normoyctic, hypochromic RBC

A

red cell loss

acute bleeding, sickle cell

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