Iron Metabolism

Question 1

inorganic substances that are required by your body in order to develop and grow properly

Answer 1

minerals

Question 2

where is iron mainly absorbed

Answer 2

stomach and duodenum

Question 3

in what form is iron soluable and reaily absorbed

Answer 3

ferrous 2+

Question 4

how much dietary iron is typically absorbed

Answer 4

10%

Question 5

those with low stomach acid absorb_____ iron

Answer 5

less

Question 6

what are the fates of absorbed Fe2+

Answer 6

• reoxidized and stored in ferritin

- bound to transferrin

Question 7

what is the major regulator of iron absorption

Answer 7

hepcidin. induces internalization and digestion of ferroportin

Question 8

what happens to old RBCs

Answer 8

recycled by phagocytes in the spleen

Question 9

what is heme broken down into

Answer 9

bilirubin

Question 10

why do pregnant women lose more Fe

Answer 10

fetal brain development. iron requirement is 9x greater

Question 11

what is the execretory mode of iron loss

Answer 11

there is none

Question 12

Iron deficiency results in what kind of anemia

Answer 12

microcytic

Question 13

hypersegmented neutrophils are typically seen in what type of anemia

Answer 13

macrocytic

Question 14

what is siderblastic anemia

Answer 14

enough iron but it isnt incorporated due to problems with red cell maturation

Question 15

what is the test for siderblastic anemia

Answer 15

prussian blue

Question 16

low iron and ferriton, high TIBC is an indication of

Answer 16

iron deficiency anemia

Question 17

normal/high iron and ferritin is an indication for

Answer 17

thalassemia

Question 18

blood test that measure the iron in the liquid part of the blood

Answer 18

serum iron

Question 19

the remaining transferrin (not being used to transport iron)

Answer 19

UIBC (unsaturated iron binding capacity)

Question 20

the serum iron plus UIBC

Answer 20

TIBC (total iron binding capacity)

Question 21

the blood test that measure the amount of iron stored in the body

Answer 21

ferritin

Question 22

a highIBC, TIBC, or transferrin typucally indicates

Answer 22

iron deficiency

Question 23

how is transferrin saturation calculated

Answer 23

serium iron / total iron binding capacity x 100

Question 24

what is the most common form of poisoning death in children < 6

Answer 24

hemochromatosis