RBC Cytoskeleton Properties Flashcards
1
Q
What is the role of spectrin?
A
Actin crosslinking
Molecular scaffold linking the plasma membrane to the actin cytoskeleton.
2
Q
What is the role of Ankyrin?
A
Linking of integral membrane proteins to actin-spectrin cytoskeleton.
3
Q
What is the role of Band 3?
A
AE
Involved in the physical linkage of CSM to the underlying cytoskeleton by binding to ankyrin and 4.2
4
Q
What is the role of protein 4.2?
A
Is an ATP-binding protein which regulates the association of protein 3 with Ankryin.