RBC Cytoskeleton Properties Flashcards

1
Q

What is the role of spectrin?

A

Actin crosslinking

Molecular scaffold linking the plasma membrane to the actin cytoskeleton.

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2
Q

What is the role of Ankyrin?

A

Linking of integral membrane proteins to actin-spectrin cytoskeleton.

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3
Q

What is the role of Band 3?

A

AE

Involved in the physical linkage of CSM to the underlying cytoskeleton by binding to ankyrin and 4.2

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4
Q

What is the role of protein 4.2?

A

Is an ATP-binding protein which regulates the association of protein 3 with Ankryin.

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