pituitary Disorders Flashcards
1
Q
Give mass effect complications of pituitary adenomas.
A
Headaches Vomiting Visual field defects Cranial nerve palsy Nausea
2
Q
Under what conditions does gigantism occur?
A
Excess GH before epiphyseal plate fusion.
3
Q
What is the most common cause of hypopituitarism?
A
Pituitary adenoma
4
Q
Under what conditions are ADH and OT production affected?
A
HT tumour, or spread to HT
Inflammatory process involved
5
Q
What are the main symptoms of diabetes insipidus?
A
Dehydration
Polyuria
Polydypsia
6
Q
Give physical changes seen in gigantism
A
Coarse facial features Broad nose Prominent supraorbital ridge Greasy skin Deep voice
7
Q
Name a GH receptor antagonist.
A
Pegvisomant
8
Q
What is the clinical presentation of pituitary apoplexy?
A
Sudden onset headache
Double vision
Cranial nerve palsy
Hypopituitarism - cortisol deficiency is the most dangerous
