Rapid Review - Classic Treatments

Question 1

Absence Seizures

Answer 1

Ethosuximide, VPA if with tonic-clonic

Question 2

Acute Gout Attack

Answer 2

NSAIDs, Colchicine

Question 3

Acute Promyelocytic Leukemia (M3)

Answer 3

All-trans vitamin A (Retinoic Acid)

Question 4

ADHD

Answer 4

Methylphenidate, amphetamines

Question 5

Alcohol Abuse

Answer 5

AA + disulfiram

Question 6

Alcohol Withdrawal

Answer 6

Benzos

Question 7

Anorexia

Answer 7

SSRIs (Really?)

Question 8

Anticoagulation during Pregnancy

Answer 8

Heparin

Question 9

GAD

Answer 9

Buspirone

Question 10

Arrhythmia in damaged cardiac tissue

Answer 10

Class IB (lidocaine, mexiletine, tocainamide)

Question 11

B12 deficiency

Answer 11

B12 (I don’t buy it)

Question 12

BPH

Answer 12

Tamsulosin, Finasteride

Question 13

Bipolar Disorder

Answer 13

Li, VPA, Carbamazepine

Question 14

Breast Cancer in Post-menopausal woman

Answer 14

Aromatase inhibitors

Question 15

Buerger’s disease

Answer 15

Smoking cessation (thromboangiitis obliterans)

Question 16

Bulimia

Answer 16

SSRIs

Question 17

Candida

Answer 17

Systemic? Amphotericin B, Nystatin (thrush, esophagitis)

Question 18

Carcinoid syndrome

Answer 18

Octreotide

Question 19

Chlamydia Trachomatis

Answer 19

Doxycycline or azithromycin (+ ceftriaxone for gonorrhea coinfection), erythromycin eye drops (ppx for infants)

Question 20

Chronic Gout

Answer 20

Allopurinol (overproducers), Probenecid (underexcretor)

Question 21

Chronic Hepatitis

Answer 21

IFN-alpha

Question 22

CML

Answer 22

Imatinib

Question 23

Clostridium Botulinum

Answer 23

Antitoxin

Question 24

C. Difficile

Answer 24

PO metronidazole/ PO Vancomycin

Question 25

C. Tetani

Answer 25

Antitoxin, vaccine booster, diazepam

Question 26

Crohn's disease

Answer 26

corticosteroids, infliximab (anti TNF)

Question 27

Cryptococcus Neoformans

Answer 27

Fluconazole (ppx in AIDS)

Question 28

Cystic Fibrosis

Answer 28

N-Acetylcysteine and anti-pseudomonal ppx (tobramycin/azithromycin)

Question 29

CMV

Answer 29

Ganciclovir

Question 30

Depression

Answer 30

SSRIs

Question 31

DI

Answer 31

Desmopressin (central); HCTZ, indomethacin, amiloride (nephrogenic)

Question 32

TIDM

Answer 32

Dietary intervention (low sugar), insulin

Question 33

TIIDM

Answer 33

Dietary intervention, oral hypoglycemics, insulin

Question 34

DKA

Answer 34

Fluids, insulin, K

Question 35

Enterococcus

Answer 35

Vancomycin/ampicillin + aminglycoside

Question 36

Erectile dysfunction

Answer 36

Sildenafil

Question 37

ER-positive breast cancer

Answer 37

Tamoxifen, raloxifene

Question 38

Ethylene glycol/methanol intoxication

Answer 38

Fomepizole (alcohol dehydrogenase inhibitor)

Question 39

H. Flu B

Answer 39

Rifampin Ppx

Question 40

Hemorrhagic cystitis

Answer 40

Mesna

Question 41

Heparin toxicity (rare)

Answer 41

Protamine Sulfate

Question 42

HER2/new-positive breast cancer

Answer 42

Trastuzumab

Question 43

Hyperaldosteronism

Answer 43

Spironolactone

Question 44

Hypercholesterolemia

Answer 44

Statins (HMG CoA reductase inhibitors, decrease endogenous cholesterol synthesis and increase LDLR)

Question 45

Hypertriglyderidemia

Answer 45

Fibrates

Question 46

Immediate anticoagulation

Answer 46

Heparin

Question 47

Infertility

Answer 47

Pulsatile Leuprolide

Question 48

Influenza

Answer 48

Amantadine/rimantadine

Question 49

Legionella pneumophila

Answer 49

Erythromycin

Question 50

Long-term anticoagulation

Answer 50

Warfarin

Question 51

Malaria

Answer 51

Chloroquine/mefloquine (for blood schizont); primaquine (for liver hypnozoite)

Question 52

Malignant Hyperthermia

Answer 52

Dantrolene- decreases intracellular Ca by binding to ryanodine receptor and uncoupling excitation and contraction of skeletal muscles

Question 53

Medical Abortion

Answer 53

Mifepristone (anti-progestin) and misoprostol (Prostaglandin analog)

Question 54

Migraine

Answer 54

Triptans (vasoconstrictors)

Question 55

MRSA

Answer 55

Vancomycin

Question 56

MS

Answer 56

Beta interferon

Question 57

TB

Answer 57

Rifampin, INH, pyrazinmide, ethambutol, streptomycin (RIPES)

Question 58

Neisseria Gonorrheae

Answer 58

Ceftriaxone (add doxy or azithro for CT)

Question 59

Neisseria Meningitidis

Answer 59

Penicillin/ceftriaxone, rifampin for ppx

Question 60

PDA

Answer 60

Indomethacin to close, misoprostol to keep open

Question 61

Pheochromocytoma

Answer 61

alpha antagonists

Question 62

PCP

Answer 62

TMP-SMX ppx

Question 63

Prolactinoma

Answer 63

Bromocriptine (DA agonist)

Question 64

Prostate cancer/uterine fibroids

Answer 64

Continuous leuprolide

Question 65

Pseudomonas Aeruginosa

Answer 65

Antipseudomonal penicillin (pip tazo) + aminoglycoside

Question 66

Pulmonary Hypertension

Answer 66

Bosentan

Question 67

Ricketsia Ricketsii

Answer 67

Tetracycline, chloramphenicol (esp in context of aplastic anemia)

Question 68

Teniae (corporis, capitis, cruris, etc)

Answer 68

Terbinafine, griseofulvin, imidazole

Question 69

Schizophrenia (negative symptoms)

Answer 69

atypical antipsychotics

Question 70

Schizophrenia (positive symptoms)

Answer 70

typical antipsychotics

Question 71

SIADH

Answer 71

Demeclocycline, Lithium

Question 72

Sickle Cell Anemia/Beta thalassemia

Answer 72

hydroxyurea (increases HgbF)

Question 73

Sporothrix schenkii (sporotrichosis- rose handler's disease)

Answer 73

oral KI

Question 74

Stable Angina

Answer 74

Sublingual Nitroglycerin

Question 75

Staph Aureus

Answer 75

Methicillin/Nafcillin

Question 76

Strep Bovis

Answer 76

Penicillin ppx (think colon cancer)

Question 77

Strep Pneumo

Answer 77

Systemic/pneumonia? Penicillin/cephalosporin. Meningitis? Vancomycin

Question 78

Strep Pyo

Answer 78

Penicillin ppx

Question 79

Strep Agalactitiae

Answer 79

screen week 35-37, intrapartum PCN for ppx

Question 80

Temporal arteritis

Answer 80

high dose steroids

Question 81

Tonic Clonic Sz

Answer 81

Carbamazepine, VPA, phenytoin

Question 82

Toxoplasma Gondii

Answer 82

Sulfonamide + pyrimethamine

Question 83

Treponema Pallidum

Answer 83

PCN. Allergic? desensitize, then PCN

Question 84

Trichomonas

Answer 84

Metronidazole (pt and partner)

Question 85

Ulcerative Colitis

Answer 85

5-ASA, infliximab (anti TNF)

Question 86

UTI

Answer 86

TMP-SMX ppx

Question 87

Warfarin OD

Answer 87

FFP, Vit K

Question 88

Wegener's

Answer 88

Cyclophosphamide, corticosteroids