Fungi

Question 0

Pseudo hyphae

Answer 0

Candida

Question 1

Dimorphism

Answer 1

Histoplasma, blastomycosis, coccidioides, sporothrix

Question 2

Moa of Imidazoles

Answer 2

Inhibit ergosterol synth

Question 3

Moa of polyene

Answer 3

Bind ergosterol

Question 4

Fungal color on koh

Answer 4

Dematiaceous-olive brown

Question 5

Fungal color on pas

Answer 5

Hot pink

Question 6

Fungal color on silver stain

Answer 6

Old rose gray to black

Question 7

Fungal color on calicofluor white

Answer 7

Bright blue white on black

Question 8

Fungal color on India ink

Answer 8

Colorless cells with clear halos from capsule on black background

Question 9

Fungal culture agar

Answer 9

Saboraud

Question 10

Test for crypto in serum/csf

Answer 10

Latex particle agglutination of capsular polysaccharide

Question 11

Spaghetti and meatballs yeast clusters with short curved septate hyphae

Answer 11

Malasezzia furfur

Question 12

Malasezzia causes fungemia in what group

Answer 12

Premies on iv lipids

Question 13

3genera of dermatophytes

Answer 13

Trichophyton, microsporum, epidermophyton

Question 14

Most serious tinea capitis

Answer 14

Favus- permanent hair loss, contagious

Question 15

Dx microsporum

Answer 15

Woods lamp - fluoresces

Question 16

Koh mount of dermatophytes

Answer 16

Arthroconidia and hyphae

Question 17

Tx of dermatophytes

Answer 17

Topical Imidazoles or tolnaftate

If skim hurts or hair involvement then oral Imidazoles or griseofulvin

Question 18

Hyphae with rosettes and sleeves of conidia

Answer 18

Sporothrix env form

Question 19

Cigar shaped yeast

Answer 19

Sporothrix in tissue

Question 20

Tx of sporotrichoxis

Answer 20

Potassium iodide in milk or itraconazole

Question 21

Who gets pulmonary sporotrichosis

Answer 21

Urban alcoholics

Question 22

Why are blood culture useful for Histoplasma

Answer 22

Bc circulates in res cell- monocytes/ macrophage

Question 23

Inhibitory mold agar

Answer 23

Saboraud with antibiotics

Question 24

Small intracellular yeast with narrow neck on bud

Answer 24

Histo

Question 25

Spelunking

Answer 25

Histo

Question 26

Bird or bat feces

Answer 26

Histo

Question 27

Calcified lesion on healing

Answer 27

Histo

Question 28

What increases relapse potential for histo

Answer 28

T cell suppression

Question 29

Spherules with endospores

Answer 29

Coccidiomycosis

Question 30

At what point in pregnancy does coccidioides disseminate

Answer 30

3 trimester

Question 31

What are good prognostic signs in coccidioides

Answer 31

Erythema nodosum and arthritis

Question 32

Rotting wood such as beaver dams

Answer 32

Blasto

Question 33

Broad base budding yeasts with double refractive cell walk

Answer 33

Blasto

Question 34

Which dimorphism is least likely to resolve on its own

Answer 34

Blasto

Question 35

Acute angles

Answer 35

Aspergillosis

Question 36

Where in lung does abpa grow

Answer 36

In mucous plugs not in tissue

Question 37

Tx of aspergillosis

Answer 37

Itraconazole or ampho b

Question 38

Germ tubes at 37 degrees

Answer 38

Candida

Question 39

Tx disseminated candida

Answer 39

Ampho or fluconazole

Question 40

Monomorphic

Answer 40

Crypto

Question 41

Pigeon droppings

Answer 41

Crypto

Question 42

Dominant aids meningitis

Answer 42

Crypto

Question 43

Tx of crypto

Answer 43

Ampho plus 5fc then fluconazole

Question 44

Ketoacidotic diabetic

Answer 44

Mucor

Question 45

Silver stained cysts in tissue

Answer 45

Pcp

Question 46

Foamy honeycomb appearance on h and e

Answer 46

Pcp

Question 47

Pcp mechanism

Answer 47

Kills type 1 pneumocytes –>proliferation of type ii–>alveolar damage and serum leak into alveoli leading to foamy exudate

Question 48

Patchy ground glass infiltrate on cxr

Answer 48

Pcp

Question 49

Tx pcp

Answer 49

Bactrim