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NAPLEX > RA > Flashcards

RA Flashcards

1
Q

methotrexate dosing

A

is weekly not daily
daily is fatal
max is 20mg/week

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2
Q

methotrexate SE

A 
M-mucositosis,myleosupression
E
T
H-hepatoxicity
O- phOtosensitivity
T
R-Renal (give bicarb to keep urine alkaline), Rash
E
X-Preg. Cat. X, Chest X-ray(pulmonary fibrosis)
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3
Q

avoid which antibiotic with methotrexate

A

bactrim, bc increase risk of mtx toxicity

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4
Q

methotrexate is

A 
an antimetabolite
and 
s phase toxic
and 
folic acid structural analog
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5
Q

washout procedure for leflunomide (arava)

A

cholestyramine 8 grams tid for 11 days

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6
Q

leflunomide, mtx, and azathioprine are

A

not to be used in pregnancy

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7
Q

allopurinol and febuxostat are

A

xanathine oxidase inhibitors

must decrease dose of azathioprine

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NAPLEX (24 decks)

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