HTN Flashcards

1
Q

CCB side effects

A

constipation
decrease heart rate
gingival hyperplasia
edema

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2
Q

CCBs have no effect on

A

the kidneys

thus they do not effect electrolytes!

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3
Q

diltiazem formulations

A

PO

IV

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4
Q

Diltiazem brand names

A
cardizem (SR, CD)
dilacor XR
diltia XT
cartia XT
tiazac
tiamate
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5
Q

verapamil brands

A

calan, calan sr, isoptin SR, verelan, verelan PM

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6
Q

verapamil formulations

A

PO and IV

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7
Q

ccb with the least headache flushing and edema

A

verapamil

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8
Q

give on an empty stomach

A

captopril
nisoldipine
moexipril

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9
Q

give with food

A

metoprolol tartrate

carvedilol

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10
Q

problem w nifedipine

A

reflex tachycardia

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11
Q

used for vasospastic (variant angina) prinzmetals

A

nicardipine

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12
Q

ER formulations

A

felodipine, nisoldipine

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13
Q

what class is metolazone

A

thiazide like diuretic

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14
Q

amiloride MOA

A

potassium sparing diuretic

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15
Q

MOA of torsemide

A

decrease nacl reabsorption in the thick ascending limb of the loop of henle

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16
Q

most ototoxic loop

A

ethacrynic acid

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17
Q

loop converstions

A
elephants fart too big 
e-50
f-40
t-20
b-1
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18
Q

lasix available formulations

A

IV, IM, PO tabs and solution

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19
Q

due to first dose phenomenon, most alpha blockers generally have to be titrated expect from some such as

A

alfluzosin, silodosin, tamsulosin

some that do: terazosin, doxasozin

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20
Q

brand of silodosin

A

rapaflo

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21
Q

prazosin brand

A

minipress

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22
Q

tamsulosin brand

A

flomax

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23
Q

prazosin MOA

A

alpha 1 adrenergic receptor blocker

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24
Q

which ALPHA 1 blocker is only approved for HTN and not BPH

A

prazosin (minipress)

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25
5 alpha reductase inhibitors
finasteride, dutasteride
26
phosphodiesterase inhibitor
slidenafil
27
propecia
1mg finasteride for MPB
28
proscar
5mg finasteride for BPH
29
dozasosin
cardura
30
dutasteride
avodart
31
lotrel
amlodipine+ benzapril
32
azor
amlodipine+olmesartan
33
dont give ___ in patients with pheochromocytoma
any beta blocker
34
tenoretic
atenolol+ chlorthalidone
35
severe HTN associated with acute MI tx
IV nitroglycerin, clevidipine, nicardipine, esmolol
36
ziac:
bisoprolol+ HCTZ
37
clevidipine is CI in which allergy
SOY and EGG just like propofol
38
clevidipine formulations
IV emulsion only
39
only ace available IV
enalapril (vasotec)
40
IV beta blocker
``` metoprolol propanolol labetolol esmolol sotalol ```
41
BB SE
bradycardia depression sedation bronchoconstriction
42
MOA of fendolopam
dopamine 1 receptor agonist
43
may raise lipids
thiazides | beta blockers
44
nipride:
nitroprusside
45
hydralazine
direct artiole vasodilator
46
nitroprusside things to know
1) iv infusion only- must be diluted prior to administration 2) stable in D5W 3) protect from light 4) may cayse cyanide toxicity
47
esmolol facts
- cardioselective - effects begin almost immediately - short duration of action - available IV
48
hydralazine:
apresoline
49
catapres tts patch should be changed how often
every 7 days
50
catapres:
clonidine
51
clonidine moa
alpha 2 adrenergic agonist
52
initial starting dose for clonidine HTN
0.1 mg at bedtime
53
clonidine formulations
patch and tablet
54
kapvay
ER clonidine for adhd
55
clonidine SE
hypotension, drowsiness, dizziness, confusions | drymouth, constipation
56
clonidine indications
HTN, ADHD, special pain management
57
thiazides can increase
uric acid
58
thiazide SE
hypercalcemia hypomag, kalemia, natremia hyperurecemia increase lipids
59
risks of high blood pressure
1) stroke 2) kidney disease 3) heart disease
60
minoxidil and hydralazine MOA
direct vasodilators
61
thiazides arent effective when crcl
is less than 30
62
can cause sprue like enteropathy
olmesartan (benicar)
63
antihypertensives available as IV
``` hydralazine diltiazem labetalol nicardipine chlorothiazide enalaprit methyldopa esmolol propanolol metoprolol clevedipine nitroglycerin nitroprusside verapamil -there are no IV arbs! ```
64
microzide:
HCTZ
65
two symptoms of hypoglycemia that are not masked with BBs
sweating and hunger
66
avoid grapefruit and the juice with which antihypertensice
CCBs!
67
exforge
amlodipine+valsartan
68
inderal
propanolol
69
which antihypertensive is constipating
verapamil
70
htn emergency bp reduction should be
less than 25 percent in the first hour
71
shortest half life ace dosed TID
captopril
72
normal heart rate
60-100
73
triamterene+hctz
maxzide or dyazide
74
aces do what to potassium
hyperkalemia
75
hyzaar
losartan+hctz
76
adalat CC
nifedipine
77
clonidine causes
rebound hypertension, do not abruptly stop
78
what is the drug of choice for portal HTN
propanolol
79
what are the beta 1 selective BBs
``` AMEBBBA atenolol metoprolol esmolol bisoprolol betaxolol bystolic (nebivolol) acebutolol ```
80
what BBs come IV
``` MAPLES metoprolol atenolol propanolol labetolol esmolol sotalol (only used for afib) ```
81
metoprolol ____ is not used for CHF
tartrate
82
carvedilol to coreg ratio
3.125 BID=Coreg CR 10mg QD 6.25 BID= Coreg CR 20 12.5=40 25=80
83
is toprol XL scored
yes
84
AFIB drugs | AV blockers
``` ABCD a-amiodarone b- bblockers c-CCBs (verapamil, diltiazem) d-digoxin ```
85
adalat cc
nifedipine