HTN Flashcards
CCB side effects
constipation
decrease heart rate
gingival hyperplasia
edema
CCBs have no effect on
the kidneys
thus they do not effect electrolytes!
diltiazem formulations
PO
IV
Diltiazem brand names
cardizem (SR, CD) dilacor XR diltia XT cartia XT tiazac tiamate
verapamil brands
calan, calan sr, isoptin SR, verelan, verelan PM
verapamil formulations
PO and IV
ccb with the least headache flushing and edema
verapamil
give on an empty stomach
captopril
nisoldipine
moexipril
give with food
metoprolol tartrate
carvedilol
problem w nifedipine
reflex tachycardia
used for vasospastic (variant angina) prinzmetals
nicardipine
ER formulations
felodipine, nisoldipine
what class is metolazone
thiazide like diuretic
amiloride MOA
potassium sparing diuretic
MOA of torsemide
decrease nacl reabsorption in the thick ascending limb of the loop of henle
most ototoxic loop
ethacrynic acid
loop converstions
elephants fart too big e-50 f-40 t-20 b-1
lasix available formulations
IV, IM, PO tabs and solution
due to first dose phenomenon, most alpha blockers generally have to be titrated expect from some such as
alfluzosin, silodosin, tamsulosin
some that do: terazosin, doxasozin
brand of silodosin
rapaflo
prazosin brand
minipress
tamsulosin brand
flomax
prazosin MOA
alpha 1 adrenergic receptor blocker
which ALPHA 1 blocker is only approved for HTN and not BPH
prazosin (minipress)
5 alpha reductase inhibitors
finasteride, dutasteride
phosphodiesterase inhibitor
slidenafil
propecia
1mg finasteride for MPB
proscar
5mg finasteride for BPH
dozasosin
cardura
dutasteride
avodart
lotrel
amlodipine+ benzapril
azor
amlodipine+olmesartan
dont give ___ in patients with pheochromocytoma
any beta blocker
tenoretic
atenolol+ chlorthalidone
severe HTN associated with acute MI tx
IV nitroglycerin, clevidipine, nicardipine, esmolol
ziac:
bisoprolol+ HCTZ
clevidipine is CI in which allergy
SOY and EGG just like propofol
clevidipine formulations
IV emulsion only
only ace available IV
enalapril (vasotec)
IV beta blocker
metoprolol propanolol labetolol esmolol sotalol
BB SE
bradycardia
depression
sedation
bronchoconstriction
MOA of fendolopam
dopamine 1 receptor agonist
may raise lipids
thiazides
beta blockers
nipride:
nitroprusside
hydralazine
direct artiole vasodilator
nitroprusside things to know
1) iv infusion only- must be diluted prior to administration
2) stable in D5W
3) protect from light
4) may cayse cyanide toxicity
esmolol facts
- cardioselective
- effects begin almost immediately
- short duration of action
- available IV
hydralazine:
apresoline
catapres tts patch should be changed how often
every 7 days
catapres:
clonidine
clonidine moa
alpha 2 adrenergic agonist
initial starting dose for clonidine HTN
0.1 mg at bedtime
clonidine formulations
patch and tablet
kapvay
ER clonidine for adhd
clonidine SE
hypotension, drowsiness, dizziness, confusions
drymouth, constipation
clonidine indications
HTN, ADHD, special pain management
thiazides can increase
uric acid
thiazide SE
hypercalcemia
hypomag, kalemia, natremia
hyperurecemia
increase lipids
risks of high blood pressure
1) stroke
2) kidney disease
3) heart disease
minoxidil and hydralazine MOA
direct vasodilators
thiazides arent effective when crcl
is less than 30
can cause sprue like enteropathy
olmesartan (benicar)
antihypertensives available as IV
hydralazine diltiazem labetalol nicardipine chlorothiazide enalaprit methyldopa esmolol propanolol metoprolol clevedipine nitroglycerin nitroprusside verapamil -there are no IV arbs!
microzide:
HCTZ
two symptoms of hypoglycemia that are not masked with BBs
sweating and hunger
avoid grapefruit and the juice with which antihypertensice
CCBs!
exforge
amlodipine+valsartan
inderal
propanolol
which antihypertensive is constipating
verapamil
htn emergency bp reduction should be
less than 25 percent in the first hour
shortest half life ace dosed TID
captopril
normal heart rate
60-100
triamterene+hctz
maxzide or dyazide
aces do what to potassium
hyperkalemia
hyzaar
losartan+hctz
adalat CC
nifedipine
clonidine causes
rebound hypertension, do not abruptly stop
what is the drug of choice for portal HTN
propanolol
what are the beta 1 selective BBs
AMEBBBA atenolol metoprolol esmolol bisoprolol betaxolol bystolic (nebivolol) acebutolol
what BBs come IV
MAPLES metoprolol atenolol propanolol labetolol esmolol sotalol (only used for afib)
metoprolol ____ is not used for CHF
tartrate
carvedilol to coreg ratio
3.125 BID=Coreg CR 10mg QD
6.25 BID= Coreg CR 20
12.5=40
25=80
is toprol XL scored
yes
AFIB drugs
AV blockers
ABCD a-amiodarone b- bblockers c-CCBs (verapamil, diltiazem) d-digoxin
adalat cc
nifedipine