immunizations Flashcards
live vaccines are CI in
pregnant and immunocompromised patients
live vaccines
C cholera O oral typhoid Z zostavax Y yellow fever I Intranasal flu V varicella R Rotavirus M MMR
increasing the interval between a vaccine series does what
it doesnt diminish the effectiveness of the vaccine but may delay protection
decreasing the interval between a vaccine series does what
interferes with antibody response and protection
antibodies/ IVIG can interfered with ___ vaccines
live, like MMR usually a waiting period
waiting period for MMR and varicella vaccines such as varivax and MMRV is 3-11 months for ___ vaccines
live
vaccine given at birth
hep b
most live vaccines witheld until ___ years of age accept
1 year, rotavirus
inactivated vaccines are started when a baby is __ onths
2, except hep b which is given at birth
tubercullin skin test also called PPD test interaction with ___ vaccines can cause a ___ negative
false
how to reduce risk of false negative with TB test and live vaccine
give live vaccine on same day as tb test
wait 1 month after live vaccine for tb test
administer skin test first, wait 48- 72 hours to get result then give live vaccine
if live vaccines arent given on the same day, how long apart
4 weeks ( 1 month )
if vaccine requires more than one dose series can be ___ but not ___
extended but not shortened
if patient has an adverse reaction to a vaccine report it to
vaers
fda’s vaccine adverse event reporting system
live vaccines can cause mild systemic reactions that can occur __ - __ days after the vaccine is given
3-21 days
minor allergic reaction tx
benadryl or hydroxyzine
severe allergic reaction tx
anaphylaxis, epinephrine
epi pen is IM or SQ
IM
how many 0.3mg auto injectors should be available in the pharmacy
3
most adults will require how many doses of epi for severe allergic reaction
1-3 doses of 0. 3mg every 5-15 min
can you give a vaccine if the patient has a slight fever
yes
can you give a vaccine if the patient is taking antibiotics
yes
exceptions :varicella, zoster, oral typhoid
can you give a vaccine if the patient has had a previous local skin reaction
yes
can you give a vaccine if the patient has immunosupressed person in the household, recent exposure to the disease or convalesence
yes
can you give a vaccine if the patient has a family history of adv events to the vaccine
yes
CI for Hep B vaccine (recombivax HB) and HPV (gardisil)
yeast!
avoid the live flu vaccine in what patient
asthma patients
varicella CI in
gelatin or neomycin allergy
what age is flu shot recommended
6 months
infants and children vaccines
3 dose hep b started at birth
other series started at 2 months: prevnar 13, DTaP, Hib, polio, rotavirus
live vaccine series started at 1 year: MMR and Varicella
no polysaccharide vaccines before age 2
health care professional vaccines
annual flu Hep B Tdap Varicella MMR
Adolescents and YA
Meningococcal (MCV4, Menactra or Menveo)
- 2 doses: 1 dose at 11-12 yo and 1 dose at 16
- first year college students (if not previously vaxed): 1 dose)
-HPV vaccine (gardisil)
age 11-12
2-3 doses depending on starting age
Tdap
first dose at age >11
sickle cell disease and other causes of asplenia (damaged or missing spleen) vaccinations
H. influenzae type b (Hib) vaccine
Pneumoccocal vaccines (prevnar 13 and 23)
- before age 65: 1 dose of prevnar 13 (if not received previously) and 2 doses of pneumovax 23
- give prevnar 13 first then 23 8 weeks later, then 23 again 5 years later
Meningococcal vaccines
- meningococcal conjugate vaccine (menactra or menveo)
- serogroup b meningococcal vaccine (bexsero or trumenba)
pregnancy vaccines
live vaccines are contraindicated
flu vaccine can be given in any trimester
tdap needs to be given once in every pregnancy (3rd trimester is optimal)
diabetes vaccines
pneumococcal vaccine
before age 65: 1 dose of pneumovax 23
hep b: age 19-59 (blood/needle protection vaccine)
causes of immunodeficenicy
chemotherapy/bone marrow transplant drugs
strong immunosupressant (etanercept, infliximab)
transplant drugs (tacrolimus, cyclosporine)
hiv w/ cd4 count <200 (aids)
systemic steroids for at least 2 weeks at 20 mg or more or 2 mg/kg prednisone daily/ equivalent
chronic renal failure
steroid dose to be immunosuppressed
1) 2 weeks or more
2) 20 mg or 2mg/kg prednisone/ equivalent daily
Tdap starts at what year
> 11 years old
shingrix for all adults age
50 and older
2 doses
2-6 months apart
wait 8 weeks (2 months) after zostavax
HPV indicated for adults less than ___and up tp ___
26 and less
and up to 45
age for pneumovax23
65