QUIZ 7 Flashcards
digestive system proper
- from innermost to outer:
- *muscosa: epithelium, lamina propria (connective), muscularis mucosae (muscle)
- *submucosa
- *muscularis externa- internal circular and external longitudinal
- adventitia or serosa
outer layer of digestive tube
- adventitia or serosa
- adventitia- loose irregular connective
- serosa- serous membrane (visceral peritoneum)
- peritoneum is the serous membrane that surrounds GI organs
- above diaphragm (like esophagus)- adventitia
- below diaphragm- intraperitoneal (all serosa) or retroperitoneal- mostly adventitia
peritoneum
- serous membrane
- parietal layer (outer)- connected to organs (abdominal walls)
- peritoneal cavity- serous fluid within
- visceral layer- inner (aka serosa)
- intraperitoneal are surrounded by peritoneum
- retroperitoneum- behind the peritoneum (not surrounded)
messentary
-double layer of visceral peritoneum
jejnum
-intraperitoneal organ
ascending colon
retroperitoneal organ
which of the following structure is a serous membrane
- peritoneum
- pericardium
- pleura
intraperitoneal structures
- surrounded by peritoneum
- below diaphragm- intraperitoneal (all serosa)
- stomach
- small intestine (most)
- cecum
- appendix
- transverse colon
- sigmoid colon
- liver
- part of large intestine
retroperitoneal structures
- behind the peritoneum (not surrounded)
- below diaphragm- retroperitoneal- mostly adventitia
- duodenum (most) - small intestine
- pancreas
- kidneys
- ascending colon
- descending colon
- rectum
- abdominal aorta
- inferior vena cava
what is the outermost layer of the GI tract called for the stomach
-serosa
lesser omentum
- branching away from serosa layer of liver
- double layer mesentery
- supports the stomach within the abdominal cavity
- vasculature and nerves that supplies GI
greater omentum
- dangly
- double layer of mesentery
- sheet on anterior side of abdomen
- fatty deposits
- adipose tissue
- fat is here
- barrier to impacts
- stretches from stomach down and connects to transverse colon
transverse mesocolon
- connects area near pancreas to the transverse colon
- supports transverse colon
- hold it towards the top of abdominal cavity
- vasculature and nerves that supplies GI
mesentery
- supplying vasculature
- large network
- folds up with the small intestine
- connects the small intestine up towards the liver and spleen
- mesentery proper
arterial blood supply of gut
- flows through mesentery, mesocolon
- arterial blood supply is separated into three components:
- foregut- supplied by the celiac artery -> stomach, liver, gallbladder, spleen, pancreas, duodenum
- midgut- supplied by superior mesenteric -> small intestine, cecum, ascending colon, transverse colon
- hindgut- supplied by inferior mesenteric -> descending colon, sigmoid colon, rectum
celiac artery
-branches into two parts
-
venous drainage of the gut
- venous blood from the gut are going towards the liver
- hepatic portal system
- all veins brings nutrients, blood, waste product, some O2 -> to the portal system -> to liver -> liver processes and metabolizes the nutrients before it goes back to heart
stomach
- digestion
- fondus- rounded superior part
- pyloris- funnel shaped -> goes into the small intestine
- antrum- wider part of pyloris
- pyloric sphincter- open to allow chyme into the small intestine
- gastric folds- present when the stomach is emptier
- three layers:
- longitudinal- smooth muscle
- circular- smooth muscle
- oblique- diagonal fibers -> mechanical digestion crushing
functions of digestive system
- oral cavity- ingestion and mastication -> salivary glands (enzymes)
- pharnx and esophagus- swallow
- stomach- digestion
- small intestine- digestion and absorption
- liver, gallbladder and pancreas- enzymes
- large intestine- absorption and storage
- rectum and anus- elimination
gastric fluid
- break down of food
- pepsin- enzyme that breaks down
- produced in the gastric glands
- mucosal layer is thick and has pits
- gastric glands produce hydrochloric acid, pepsinogen, gastrin, mucus
- acidic
- fluid is high- for one liter of food -> 3-4 liters of fluid leave
gastric ulcers
- thick mucosa layer protects the stomach
- acid eats away at the stomach when the mucosa layer wears away
- burning
- increases chance of cancer
- caused by large density of helicobacter pylori
- if helicobacter pylori produces a basic substance that protects -> if there is too much there is a reduction of mucosa layer -> ulcers (near duodenum usually)
small intestine
- duodenum descending posteriorly into the retroperitoneal space
- enters the jejunum- absorption
- enters the ilium -> ileocecal valve -> cecum (large intestine)
- mucosa layer and submucosa layer form ridges (especially jejunum) -> plicae circularis- slows down material and increase SA for absorption
- within membranous layer of mucosa layer there is villi- has arteries, veins, lacteals (transport fatty molecules)
- microvilli are on the villi- further increase the SA of small intestine
- deep to submucosa- the muscularis layer -> two layers: inner circular and outer longitudinal -> peristalsis
- villi- simple columnar epithelial cell
- narrow diameter (actually longer than large intestine)
duodenum
- c-shaped and fixed in place
- entrance of bile duct
- entrance of pancreatic duct
- receives chyme from stomach
- mostly retroperitoneal- bound to abdominal
- pyloric sphincter separating from stomach
- major duodenal papilla of vater -> bile duct and pancreatic duct comes from here
- duodenojejunal flexure- where the duodenum and jejunum meet
- basic mucosa
jejunum
- coiled and freely mobile
- handing from mesentery
- wide lumen with plicae circularis
- intraperitoneal
- thick walled
- long vasa recta (arterial supply)
ileum
- coiled and freely mobile
- narrow lumen, largely smooth inner lining
- thin walled
- short and numerous vasa recta
- intraperitoneal
- peyers patches- pick up pathogens -> immune response
vasa recta
- arteries that come off the arcades
- ileum they are short and frequent
- jejunum they are long
which portion of the small intestine are retroperitoneal
duodenum
pancreas
- regulation of acidity
- endocrine organ
- cell within pancreas are exocrine -> make digestive enzymes and bicarbonate
- 95% of tissue = exocrine acini cells
- 5% of tissue = endocrine islet cells -> insulin and glucagon secretion (metabolism and homeostasis)
liver and gallbladder
- produces bile
- bile transferred into duodenum to help with digestion
- liver is closely bound to abdominal diaphragm
- right side of liver is larger (right lobe)
- falciform ligament separate the right and left lobe
- connects to ligamentum teres
- inferior vena cava receives blood from hepatic veins
- porta hepatis: portal vein (receives blood from other organs), hepatic artery (receives oxygenated blood), common bile duct
- cystic duct connects to gall bladder
- caudate lobe- in between ligamentum teres and inferior vena cava
- quadrate lobe
- filter blood from intestines
- metabolism of: carbs, fats, proteins
hepatic lobules
- hepatic lobule- functional unit
- portal triads
- central vein in the middle- take up the metabolites and send it to the inferior vena cava to the body
- hepatocytes- filter blood from intestines and metabolism of carbs, fats, proteins
- portal vein is not fully deoxygenated -> also oxygenates
- hepatic artery that comes from descending aorta is mostly oxygenating
- bile duct- sends the bile to the small intestine
- bile caniliculi- allow for transmission of bile into the duct
- hepatic vein- transport fluid out to the inferior vena cava
gall bladder and biliary tree
- left and right hepatic duct -> common hepatic duct -> bile duct or cystic duct to gall bladder
- gall bladder is storage site for bile
which vessels/ducts carry fluid away from the hepatic lobules
- *bile duct
- *central vein- receives blood within hepatic lobules with metabolites into the inferior vena cava
- *hepatic vein
- hepatic artery brings blood towards the hepatic lobules
large intestine
- transverse mesocolon- peritoneum -> suspend
- from the ileum material is moved to cecum
- cecum is first part of large- storage
- vermiform appendix- lymphatic, repopulates normal flora
- ascending colon- right side,
- right colic (hepatic flexure)
- transverse colon
- left colic (splenic) flexure
- descending colon
- sigmoid colon
- rectum
- anal canal
- anus
teniae coli
- longitudinal layer of the large intestine doesnt go around the whole tube
- there is a strip of the teniae coli
- helps with peristalsis
intraperitoneal: large intestine
- cecum
- vermiform appendix
- transverse colon
- sigmoid colon
retroperitoneal: large intestine
- ascending colon
- rectum
- anal canal
- anus
- descending colon
ileocecal orifice
- between ileum and cecum
- controls flow of ileum into cecum
haustrum
- chambers or units in the large intestine
- semilunar folds between the haustrum
epiploic appendages
- fatty structures associated with the teniae coli
- within peritoneum
- dangling
vermiform appendix
- McBurney’s point- incision
- 1/3 distance of iliac spine and belly button
hirschsprings disease
- innervation of large intestine that is associated with smooth muscle contraction doesnt go all the way to rectum
- no nerve impulse to parts of large intestines
- no way of excretion
- no way of peristalsis
rectum and anal canal
- sigmoid colon -> rectum
- transverse rectal folds/valves of houston- hold fecal matter in place so we can pass gas without stool
- levator ani (pubococcygeus)- pelvic diaphragm -> supports
- anal columns- as solids pass anal columns gland are compressed and fluid is produced
- internal anal sphincter- smooth (sympathetic)
- external anal sphincter- skeletal
- at level of S3
- puborectalis- muscle around the rectum- regulates defication
excretion
- internal and external anal sphincter must be relaxed for defecation
- puborectalis- acts as a sling around the rectum -> moves it to the side and prevents defecation when contracted
- when puborectalis is relaxed -> defecation
- sitting- puborectalis is still pulling against
- squatting- loosens the puborectalis sling around rectum
sympathetic nervous system signals are associated with what function within the anal canal
- contract internal anal sphincter
- sympathetic fight or flight prevents defecation
- autonomic is associated with smooth muscle rather than skeletal (external anal sphincter)
innervation of anal sphincter
Internal Anal Sphincter -sympathetic: below L1 -parasympathetic: S2-S4 External Anal Sphincter -somatic motor : S2-S4
rectum vessels
- internal iliac
- middle rectal
- inferior rectal
- superior rectal
- middle rectal
- inferior rectal
urinary system
- stores and excretes urine
- removes waste products from the blood
- maintains ion balance and acid base balance
- regulates blood and interstitial fluid volume
- regulates erythrocyte production (based on O2 levels)
components of urinary system
- kidney- produce urine
- ureter- transport urine
- bladder- store urine
- urethra- transport urine
ureter
- collects urine from bladder
- anterior to rectum
kidneys
- in abdominal cavity
- retroperitoneal
- posterior to digestive organs
- asymmetrical- right kidney is a bit lower compared to left bc the liver is so large
- right kidney is posterior to: liver, hepatic flexure, ascending colon
- left kidney is posterior to: spleen, stomach, splenic flexure, descending colon
- kidneys are anterior to: ribs, muscles of the spine, abdominal back muscles
- regulate pH, hydration, eliminating waste,
kidney: well cushioned
- surrounded by protective tissue and fat
- pararenal fat- surrounding connective tissue
- renal fascia- surround pararenal fat
- perienal fat-
- renal capsule
- renal (fibrous) capsule- connective tissues surrounding kidney, protecting it from trauma and pathogens
- renal fascia- connective tissue anchoring kidney to posterior abdominal wall
left kidney
- T11-L2
- 11th and 12th ribs
- anterior of quadratus lumborum and psoas major
right kidney
- T12-L3
- 12th rib
- anterior of quadratus lumborum and psoas major
vasculature of kidneys
- closely associated with major blood vessels
- left and right renal artery- supply blood into kidneys
- renal veins- dumps into the inferior vena cava -> heart
- vein and artery connect at hilum
- renal artery segments into segmental arteries -> interlobar arteries (go around laterally on the pyramids) -> meet superficially on the arcuate artery (anastomoses) -> interlobular artery (towards the nephrons of the cortex) -> nephrons -> filter -> interlobular veins -> arcuate veins -> interlobar veins -> segmental veins
anatomy of the kidney
- vein, ureter, and artery connect at hilum- indent
- medulla- renal pyramids (internal)
- medulla is broken up into 6-8 different pyramids
- vasculature surrounds the pyramids
- cortex- renal columns (superficial)
- renal papilla- end of renal pyramid
- as soon as urine leaves the renal pyramid it enters the minor calyx and major calyx -> renal pelvis
- renal pelvis is collecting all the urine from one kidney
- renal sinus- concave hollow area, where you find the pelvis, the calyx, and vasculature
what blood vessel receives blood from multiple arcuate veins
-interlobar vein
nephrons
- major functional unit of kidney
- produces urine (filter blood)
- > 1 million nephrons in each kidney
- spans the boundary between renal cortex and medulla
- vascular and tubular components
nephron vasculature
- efferent arterioles
- interlobular artery- away from arcuate arteries into the cortex (away from medulla)
- afferent arterioles- bring blood to one specific nephron -> into glomerulus
- glomerulus- first filtration
- from the glomerulus -> efferent arterioles -> into the peritubular capillaries surrounding the tubes within the cortex
- descends down around the nephron loop as vasa recta (parallel blood vessels)
- venules -> interlobar veins
tubular component
- cortical nephrons- 85% (most of the nephrons) - nephron loop is short- doesnt go far into the pyramids
- juxtamedullary nephrons- 15%- descend deep into the medulla
filtration
- blood in the glomerulus (high pressure) -> push material (filtrate) out into the bowmans capsule (renal corpuscle)
- proximal convuluted tubule (PCV)- associates with capillary network- transport of material between PCV
- water getting send back into the blood stream via capillaries
- distal convoluted tubule- tubular secretion- active transport of things out of the blood into the urine (waste product)