QUIZ 5 Flashcards
visceral efferent: autonomic
- sympathetic
- parasympathetic
somatic vs autonomic: type of control
- somatic- voluntary (conscious)
- autonomic- involuntary (unconscious)
- you can control the autonomic by some extent through meditation (raise heart beat)
somatic vs autonomic: type of effector organ that it innervations
- somatic- skeletal muscle
- autonomic (visceral efferent)- smooth, cardiac glandular
somatic vs autonomic: number of neurons from CNS to effector organ
- somatic- only one neuron (myelinated) runs out of the CNS from the spinal cord directly to synapse on the effector organ
- autonomic- two -> preganglionic (myelinated) and postganglionic (unmyelinated)
parasympathetic
- peripheral portion of a parasympathetic -> preganglionic neuron is longer
- preganglionic neuron long
- postganglionic neuron short
- ganglion closer to target organ (in the wall of the target organ)
- rest and digest
- preganglionic secretes ACh
- postganglionic secrete ACh
- outflow cranially (4 cranial nerves) and caudal/sacral (S2,S3,S4)
- preganglionic cell bodies (brainstem or S2-S4 lateral horns)
- ganglion- terminal ganglia and intramural ganglia
- pelvic splanchnic nerve
sympathetic
- preganglionic neuron short
- postganglionic neuron long
- ganglion closer to CNS
- fright, flight, fight
- preganglionic secretes ACh
- postganglionic secrete norepinephrine
- outflow from the CNS from the spinal cord (T1-L2)
- preganglionic cell bodies- T1=L2 (lateral horn)
- ganglion- paravertebral, prevertebral (celiac, superior mesenteric, inferior mesenteric)
- sympathetic chain (trunk)
- sympathetic splanchnic nerve (pass through the sympathetic chain to synapse at the prevertebral ganglion)
- sympathetic organ nerve
bright light on retina
- picked up by CNS
- brain nucleus
- synapse at ciliary ganglion
- ACh release
- received by nicitonic receptors
- pupil contriction
parasympathetic innervation
-cranial nerves CNIII ,CN VII, CN IX , CNX and S2-S4
parasympathetic ganglia
- terminal ganglion- ganglion located near the target effector
- intramural ganglion- ganglion located in the wall of the target organ (pelvic sphlancnic nerves or vagus nerve
cranial terminal ganglion
- ciliary ganglion
- pterygopalatine ganglion
- submandibular ganglion
- otic ganglion
oculomotor nerve CNIII
- parasympathetic
- terminal ganglion- ciliary ganglion
- target effectors- ciliary muscle and constrictor pupillae
ciliary mucles
- has parasympathetic innervation starts in midbrain and travels with oculomotor nerve and synapses at ciliary ganglion -> postganglionic fiber travels along V1 fibers and ends at ciliary muscle
- sympathetic- cell bodies at T1-L2 -> going through ventral root of spinal nerve
- paravertebral ganglion and up the sympathetic chain
- superior cervical ganglion organ nerve ciliary muscle
facial nerve CN VII
-2/3 branches include parasympathetic
-ganglion- pterygopalatine
-target- lacrimal gland
-chorda tymapni
-
which major foramen does the facial nerve pass through before it splits into 3 distinct branches
-internal acoustic meatus
submandibular gland
- parasympathetic- pons -> facial nerve (chorda tympani) -> submandibular ganlgion -> V3 fibers (lingual nerve) -> submandibular gland
- sympathetic -> T1-L2 -> white ramus -> paravertebral ganglion -> up sympathetic chain -> superior cervical ganglion -> organ nerve -> submandibular gland
glossopharyngeal nerve
- parasympathetic
- terminal ganglion- otic ganglion
- target effectors- parotid gland
vagus nerve
- transmits a lot pf parasympathetic (80% of all parasympathetic preganglionic axons are transmitted through the vagus nerve)
- parasympathetic-
- preganglionic axons project to intramural ganglia of many organs (heart, tracheobronchial tree, most abdominal organs to splenic flexure)
splenic fixture
-between transverse and descending colon on the left side of the body
stomach
- parasympathetic- medulla oblongata -> vagus (abdominal aortic plexus) -> intramural ganglion -> intramural ganglion -> short nerves -> stomach
- sympathetic- T1-L2 (T5-T9) -> white ramus -> paravertebral ganglion -> splanchnic nerve -> celiac ganglion -> organ nerve -> stomach
collateral abdominal ganglia
- there are 3
- T5-T9 -> celiac ganglion (stomach, liver, gallbladder, spleen, pancreas, kidney)
- T9-T12 -> superior mesenteric ganglion (small intestine and first part of large intestine)
- T12-L2 -> inferior mesenteric ganglion (lateral part of large intestine, rectum, pelvic organs)
- distribute the postganglionic fibers to the abdominal contents (foregut, midgut, hindgut)
parasympathetic outflow: S2-S4
- sacral outflow- S2-S4
- pelvic splanchnic nerves come off- 3 (preganglionic travel here)
- hypogastric plexus- preganglionic nerves merge here)
- preganglionic axons project/synapse to intramural ganglia of almost all organs inferior to the splenic flexure:
- descending colon
- rectum
- bladder
- reproductive organs
vagus
- comes out of the skull and descends
- 80% of parasympathetic innervation
- thorax and abdomen
bladder
- parasympathetic:
- S2-S4
- pelvic splanchnic nerves
- intramural ganglion
- short nerves
- bladder
- sympathetic:
- T1-L2 (T10-L2
- white ramus
- paravertebral ganglion
- down sympathetic chain
- splanchnic nerve
- inferior mesenteric ganglion
- postganglionic fiber
- bladder
S2-S4 (preganglion)
- goes through hypogastric plexus
- targets lower digestive
- pelvic (various)
Vagus (CN X): preganglion
- goes through cardiac plexus -> targets heart
- goes through pulmonary plexus -> tracheobronchial tree
- goes through esophageal plexus -> esophagus, stomach
- goes through abdominal aortic plexus -> abdominal (various)
autonomic plexus
- usually include both sympathetic and parasympathetic axons,
- no neural signaling occurs between these systems though
parasympathetic nervous system function
- rest and relaxation responses
- energy conservation
- maintaining resting homeostasis
- counteracts sympathetic responses
- always “on”
- some organs have more parasympathetic and sometimes more sympathetic signaling
- discrete and localized effects: activation of a single organ -> no mass activation (unlike symp)
examples of parasympathetic effects
- heart: decreased heart rate, weakened contractions, high blood pressure
- respiratory system: decreased diameter of airways
- face: pupil constriction, visual accommodation (close vision), increased saliva production
- digestive: increased smooth muscle motion, increased secretory activity
- bladder: smooth muscle contraction
- reproductive organs: erection of penis of clitoris (you feel safe)
visceral afferent
- unlocalized sensation (referred pain)
- subconscious receptor signaling (ex. CO2 concentration)
- provokes responses from autonomic responses
- associated with neurons of most internal organs
- go back to CNS or reflex arch in CNS to provokes a response
- pain types:
- ischemia (lack of O2) -> symp
- cramping -> symp
- distension (full tummy or full bladder) -> parasympathetic
- inflammation -> symp
somatic sensory
- localized sensation
- conscious perception (usually)
- associated with sensory neurons of skin, muscles and tendons
visceral afferent pathways
- follows path taken by sympathetic efferent
- afferent neurons DO NOT synapse in prevertebral or paravertebral ganglia (single peripheral neuron to CNS)
- afferent neuron cell bodies in posterior root ganglion of spinal nerve
- peripheral receptor -> CNS
referred pain
- particularly strong visceral sensations are frequently perceived consciously as pain in specific dermatome regions
- relevant visceral sensory fibers enter the spinal cord at the same level as somatic sensory fibers of that dermatome
- somatic sensory signal at the same level of spinal cord as visceral sensory signal
- appendix inflammation -> pain in belly button
visceral afferent pathways
- follows path taken by sympathetic efferent
- TWO EXCEPTIONS:
- follow path taken by parasympathetic in
1. tracheobronchial tree, heart, abdominal viscera -> follows vagus - distension of pelvic organs (bladder, uterus) -> follows pelvic splanchnic nerves
visceral sensory signal resulting from ischemia of the bladder is collateral to which nerve
- sacral splanchnic nerves (sympathetic)
- distension follows pelvic splanchnic nerves
- ischemia travels with sacral splanchnic nerves (sympathetic)
labor pain
- visceral afferent
- cervical distension (cervix dilation) -> follow a parasympathetic pathway -> pelvic splanchnic via S2-S4
- cramping of uterus (uterine contraction) -> follow a sympathetic pathway T10-L1
visceral afferent function
-provoke an autonomic response
-ex. micturition:
-distension of bladder
-visceral afferent signals CNS
-synapse at spinal cord
-parasympathetic
-
sensory receptors are specialized
- only certain kinds of stimulation
- convert stimulation to nerve impulse
general somatic senses
- touch
- temperature
- pain
- proprioception
special somatic senses
- smell (chemoreceptors)
- taste (chemoreceptors)
- vision (photoreceptors)
- hearing (mechanoreceptors)
- equilibrium (mechanoreceptors)
chemoreceptors
- specific molecules in fluid
- taste, smell
thermoreceptors
- identify changes in temperature
- free nerve endings- epidermis
- not all nociceptors are also thermoreceptors
- same free nerve endings at thermoreceptors in the skin
nociceptors
- pain receptors
- chemical changes
- free nerve endings- epidermis
- not all nociceptors are also thermoreceptors
- same free nerve endings at thermoreceptors in the skin
mechanoreceptors
- distortion of plasma memberane (various)
- baroreceptors- blood vessel stretch
- touch
- proprioception
- tactile corpuscule- papillary layer of dermis, discriminative touch (fine touch)
- lamellated corpuscule- reticular layer of dermis, coarse touch, deep pressure, vibration
- proprioception in mechanoreceptors is in sensory nerve ending of muscle spindles- detect stretching of the surrounding muscle fibers (change in plasma membrane)
photoreceptors
- light intensity, color, motion
- rods, cones
what kind of sensory receptors are associated with sensing the movement of arm hairs when we put on a shirt in the morning
-mechanoreceptors
special senses: smell: chemoreceptors
- CN I
- olfactory mucosa
- mucus membrane of olfactory epithelium -> chemoreceptors are here
- lines superior region of nasal cavity
- traps and dissolves an odorant
- stuffy nose -> odorants need to make their way up to the mucus membrane
- olfactory receptors- cells stimulated by odorants
- modified bipolar neurons
- each bind to a small number of odorants
- humans can perceive 1000s of odorants
- supporting cell- sustain and support receptor cells
- basal cells- cell population that continuously replace receptor cells (receptors are damaged by chemicals)
- bipolar neurons transmit signal (after binding to olfactins) through the cribriform plate to the olfactory bulb
- olfactory bulb- synapse of CN1 with interneurons, enlargement of olfactory tract (cell bodies)
why does sniffing help us to perceive smells more strongly
- brings more odorant to the olfactory mucosa
- increases air pressure and turbulence -> allows larger odorants to come to the olfactory mucosa
special senses: taste: chemoreceptors
- paillae- tissue elevations of the tongue composed of epithelium and connective tissue (there are 4 on tongue)
- filiform papilla- pointy, move food around by friction, bumps
- fungiform papilla- within this papillae there are taste buds, rounded
- vallate papilla- most taste buds on the side walls of this papilla are here, V shape, back of tongue
- foliate papilla- childhood taste buds are in here
- taste buds- containing gustatory receptors (chemoreceptors) are distributed within fungiform and vallate papillae of adults
- bind to chemicals