Quiz 2 - Werners Flashcards

1
Q

cyclophosphamide; dacarbazine and lomustine are all metabolized in the

A
  • liver
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2
Q

chlorambucil has lowest

A
  • chance of toxicity
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3
Q

ifosfamide is most

A
  • potent
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4
Q

carboplatin can be used in

A
  • cats
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5
Q

5-fluorouracil cannot be used in

A
  • cats
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6
Q

cystosine arabinoside crosses

A
  • BBB
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7
Q

doxorubicin is most

A
  • cardiotoxic
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8
Q

actinomycin D and epirubicin are

A
  • not cardiotoxic
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9
Q

vinca alkaloids alone are used for treatment of

A

TVT

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10
Q

L-asparaginase can cause

A
  • pancreatitis
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11
Q

drugs that end in (-nib) are used to treat

A
  • mast cell tumors
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12
Q

tamoxifen effectiveness depends on

A
  • number of receptors

- for mammary carcinomas

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13
Q

delmadinone is used for

A
  • perinanal gland tumors
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14
Q

butorphanol is used in what species

A
  • horses
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15
Q

anti-tussive are used for

A
  • severe non-producing cough
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16
Q

acetylcysteine disrupts what

A
  • sulfhydryl bonds
17
Q

atropine is used for

A
  • non-specific (emergencies)
18
Q

butylscopolamine is used for

A
  • COPD in horses
19
Q

isoprenaline is an emergency

A
  • bronchodilator
20
Q

which drugs can inhibit uterine contractions and result in sperm abnormalities

A
  • b2-agonists
21
Q

which drugs maintain effect of B2-agonists

A
  • glucocorticoids
22
Q

4 classes of drugs that are prohibited in food producing animals

A
  • antibiotics
  • hormones/steroid
  • anti-inflammatory drugs
  • anti-viral drugs
23
Q

sulphonamide is prohibited in

A
  • dairy cattle
24
Q

what sulphonamides are NOT prohibited in dairy cattle (3)

A
  • sulfadimethoxine
  • sulfabromonethazine
  • sulfaethoxypyridazine
25
Q

phenylbutazone is prohibited in

A
  • female dairy cattle > 20 months
26
Q

cephalosporins are prohibited in

A
  • cattle, swine, chickens, turkeys
27
Q

what cephalosporins are NOT prohibited in food animals

A
  • cephapirin
28
Q

adamantane & neuraminidase inhibitors are prohibited in

A
  • chickens, turkeys, duck
29
Q

fenbendazole (fenbental) is 1st choice for what

A
  • treatment of Giardiasis
30
Q

quinacrine is used for

A
  • resistant giardiasis
31
Q

paromomycin inhibits

A
  • protein synthesis at 30S
32
Q

amprolium-sulfadimethoxine is sued for

A
  • dogs only to treat coccidiosis
33
Q

polyether ionophores MOA

A
  • changes in membrane integrity and internal osmolality
34
Q

side effects of polyether ionophores

A
  • cardiovascular especially in equids and guinea fowl
35
Q

imidocarb dipropinoate used for

A
  • canine babesiosis
36
Q

drugs against sarcocoystis neurona

A
  • traizine derivatives

- nitrothiazole derivatives

37
Q

nitroimidazoles are effective against what kind of luminal protozoa

A
  • luminal

- extra-luminal

38
Q

drugs effective against coccidian

A
  • sulfonamides
  • hydroquinolones and naphthoquinones
  • thiamine analogues
  • polyether ionophores