P16 - GI Part 3 Flashcards

1
Q

emolient laxatives MOA

A
  • softens and lubricates fecal mass
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2
Q

emolient drugs (3)

A
  • mineral oil
  • docusate sodium
  • white soft parafin
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3
Q

mineral oil side effects and what dont you use with us

A
  • don’t use with docusate sodium

- lipid pneumonia

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4
Q

white soft parafin is used for

A
  • hairball removal in cats
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5
Q

bulk-forming laxatives MOA

A
  • absorbs water and swells -> form emollient gell -> increases bulk -> distention -> peristaltic activity
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6
Q

bulk-forming laxatives drugs (5)

A
  • methylcellulose
  • carboxymethylcellulose sodium
  • plantago seed
  • bran
  • psyllium granules or powder
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7
Q

psyllium granules or power is used for

A
  • impactions due to sand
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8
Q

saline (osmotic) purgatives MOA

A
  • retain or attract water into intestinal lumen
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9
Q

saline (osmotic) purgatives not to be used in

A
  • dehydrated animals
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10
Q

saline (osmotic) purgatives drugs (5)

A
  • magnesium sulphate
  • sodium sulphate
  • milk of magnesia
  • hypertonic solutions
  • lactulose
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11
Q

lactulose is used for

A
  • constipation and hepatic encephalopathy
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12
Q

neuromuscular purgatives MOA

A
  • stimulates neuromuscular tonicity -> increase contraction
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13
Q

neuromuscular purgatives drugs (4)

A
  • cholinergic agents
  • vasopressin
  • oxytocin
  • PGE2a - PG analogs
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14
Q

irritant (stimulant) cathartics MOA

A
  • stimulates local myenteric center

- fluid accumulates in intestinal lumen

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15
Q

irritant (stimulant) cathartics drugs (2)

A
  • castor oil

- anthroquinones

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16
Q

castor oil active drug

A
  • ricinoleic acid
17
Q

anthraquinones active drug

A
  • aglycones (emodins) -> plant toxicity
18
Q

side effects of repeated dosages of anthraquinones in horses

A
  • causes superpurgation
19
Q

enema MOA

A
  • introduction of solutions into rectum to initiate defecation reflex
20
Q

phosphates are contraindicated in what species

A
  • cats -> increase P and decrease Ca
21
Q

in foals with meconium retention what drugs can you use (3)

A
  • docusate sodium
  • mineral oil
  • 4% solution acetylcysteine - refractory impactions
22
Q

drugs for the treatment of frothy bloat

A
  • dimethicone
  • poloxalene
  • docusate sodium
  • vegitable oil
23
Q

why is fish oil contraindicated for treatment of frothy bloat

A
  • stabilizes oil
24
Q

cholagogues effect on liver

A
  • contracts gallbladder
25
Q

choleretics effect on liver

A
  • stimulates secretion of bile by hepatocytes