P18 - Respiratory Pharmacology Flashcards
anti-tussives MOA
- suppresses medullary cough center
anti-tussives side effects
- vomiting, depression
anti-tussives drugs (4)
- codeine & hydrocodone
- butorphanol
- dextromethorphan
- lidocaine can be used
anti-tussives used for
- severe non-productive cough
modifying airway mucus consistency MOA
- breaks up mucus
- increases mucus gland evacuation and production
modifying airway mucus consistency drugs (3)
- acetylcysteine
- bromhexine
- dembrexin
home remedies work better than what drugs
- drugs that modify airway mucus consistency
anticholinergics MOA
- parasympathetic system
anticholinergics drugs (3)
- atropine
- butylscopolamine
- ipratropium bromide
which anticholinergic is used for emergencies
- atropine
sympathetic amines MOA
- sympathetic systems
sympathetic amines side effects (3)
- arrhythmias
- agitation
- nervousness
sympathetic amines drugs (5)
- adrenaline
- isoprenaline
- xanthine
- methylxanthine
- theophylline
sympathetic amine used as an emergency bronchodilator
- isoprenaline
B2-agonist MOA
- activation of adenylate cyclase
- enhances cAMP production
- activation of PKA
B2-agonist side effects
- decrease receptors
- sperm abnormalities
- tocolytic (inhibit contractions of uterus)
B2-agonist drugs (4)
- clenbuterol
- salbutamol
- albuterol
- terbutaline
what B2-agonist is forbidden in food animals
- clenbuterol
what class of drugs can also be used to increase muscle and decrease fat
- B2-agonist
mast cell stabilizers MOA
- prevent release of histamine -> decrease inflammation
mast cell stabilizers drugs (2)
- sodium cromoglicate
- nedocromil sodium
glucocorticoids MOA
- reduce inflammation by inhibiting mediator release
glucocorticoids side effects
- secondary viral, fungal or bacterial infections
glucocorticoids drugs (4)
- prednisone/prednisolone
- fluticasone
- beclomethasone
- dexamethasone
which class of drugs maintain the effect of beta 2 agonist
- glucocorticoids
