P20 - Antiprotozal Flashcards
treatment of giardiasis with MOA of DNA damage (3); and which one can be carcinogenic
- metronidazole - can be carcinogenic
- tinidazole
- ipronidazole
treatment of giardiasis with MOA of interaction with B-tubulin (2)
- fenbendazole -> prodrug fenbental - 1st choice
- albendazole
treatment of giardiasis with MOA interference with cell membrane (1)
- quinacrine (used for resistant)
treatment of giardiasis with MOA of production of free radicals (1)
- furazolidone
treatment of leishmaniasis 1st line drugs (4)
- allopurinol
- meglumine antimonate
- sodium stibogluconate
- amphotericin B
allopurinol MOA
- prevents uric acid
treatment of leishmaniasis 2nd line drugs (3)
- metronidazole with enrofloxacin
- paromomycin
- ketoconazole
paromomycin MOA
- inhibit protein synthesis at 30s
sulphonamides MOA
- inhibition of early steps in folate synthesis
diaminopyrimidines combined with sulphonamides (2)
- trimethoprim
- ormetoprim
treatment of coccidiosis MOA thiamine analogue (2)
- amprolium
- amprolium-sulfadimethoxine
treatment of coccidiosis MOA oxygen free radicals (1)
- furazolidone
treatment of coccidiosis MOA apicoplast interactions (1)
- ponazuril
treatment of coccidiosis MOA folic acid synthesis (2)
- sulfadimethoxine
- trimethoprim-sulfonamide
treatment of coccidiosis that is used in dogs only (1)
- amprolium-sulfadimethoxine