Quiz 1 Flashcards

1
Q

Bacterial Cell Wall Synthesis Drugs

A
  • beta-lactams
  • Bacitracin
  • Vancomycin
  • Cycloserine
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2
Q

Cell Membrane Drugs

A
  • Polymyxin B

- Colistin

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3
Q

Protein Synthesis (30s) drugs

A
  • Tetracycline

- Aminoglycoside

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4
Q

Protein Synthesis (50s) drugs

A
  • Chloramphenicol
  • Macrolides
  • Lincosamides
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5
Q

Nucleic Acid Synthesis Drugs

A
  • Fluorquninolones
  • Metronidazole
  • Rifampin
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6
Q

Folic Acid Synthesis Drugs

A
  • Sulfonamides

- Diaminopyrimidines

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7
Q

Enteric Sulfonamides

A
  • Succinylsulfathiazole
  • Sulfasalazine
  • Sulfaquinoxaline
  • Sulfaguanidine
  • Phthalylsulfathiazole
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8
Q

Topical Sulfonamides

A
  • Silver sulfadiazine
  • Mafenide
  • Sulfacetamide
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9
Q

Ophthalmic Sulfonamides

A
  • sulfacetamide
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10
Q

Diaminopyrimidines

A
  • ormetoprim
  • pyrimethamine
  • trimethoprim
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11
Q

beta lactam antibiotics

A
  • penicillin
  • cephalosporin C
  • carbapenems
  • monobactams
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12
Q

Bacteriostatic Drugs

A
  • tetracyclines
  • chloramphenicol
  • macrolides
  • lincosamides
  • sulfonamides
  • diaminopyrimidines
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13
Q

Penicillinase-resistant penicillin (good oral)

A
  • Oxacillin
  • Cloxacillin
  • Dicloxaxillin
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14
Q

Broad-spectrum penicillin

A
  • amoxicillin

- ampicillin

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15
Q

extended spectrum/anti-pseudomonal penicillin

A
  • ticarcillin
  • carbenicillin
  • piperacillin
  • mezlocillin
  • azlocillin
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16
Q

possess cephamycin group and effective against anaerobic microbes

A
  • cefotetan

- cefoxitin

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17
Q

treats opthalamic and mastitis

A
  • cefalonium
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18
Q

metabolized to desfuroylceftiofur

A
  • cefitiofur
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19
Q

fourth generation cephalosporin

A
  • cefepime

- cefquinome

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20
Q

common name for Convenia, long 1/2 life

A
  • cefovecin
21
Q

beta-lactamase inhibitor drugs

A
  • cavulanic acid
  • sulbactam
  • tazobactam
22
Q

Adverse effects of aminoglycosides

A
  • nephrotoxicity
  • ototoxicity (cats - vestibular; dogs - auditory)
  • neuromuscular blockade
23
Q

Natural tetracyclines

A
  • chlortetracycline
  • tetracycline
  • oxytetracycline
24
Q

semisynthetic tetracyclines

A
  • doxycycline

- minocycline

25
Q

adverse effects of tetracycline

A
  • esophageal lesions - cats
  • cardiac arrhythmias - horses
  • alters commensal microflora - horses
  • tooth mottling
  • growth retardation
  • hypersensitivity and drug fever - cats
26
Q

Chloramphenicol derivatives

A
  • thiamphenicol

- florfenicol

27
Q

adverse effects of chloramphenicol

A
  • does dependent bone marrow suppression
  • aplastic anemia in humans
  • gray baby syndrome
28
Q

macrolide drugs

A
  • erythromycin
  • tilmicosin
  • tylosin
  • tulathromycin
  • tiamulin
  • azithromycin
  • clarithromycin
29
Q

macrolides oral absorption

A
  • enteric coated oral formulation
30
Q

macrolides that are Type III

A
  • tulathromycin

- azithromycin

31
Q

lincosamide drugs

A
  • lincomycin

- clindamycin

32
Q

lincomycin treats

A
  • mycoplasma
33
Q

clindamycin treats

A
  • toxoplasma gondii
34
Q

macrolides adverse effects

A
  • oral administration contraindicated in hind gut fermentors
35
Q

fluoroquinolones new generation

A
  • premafloxacin

- pradofloxacin

36
Q

fluroquinolone mechanism of action

A
  • inhibits bacterial DNA gyrase/type II topoisomerase
37
Q

fluroquinolone distribution

A
  • bone
  • prostate
  • skin
  • rapid accumulation in macrophages and neutrophils
38
Q

fluroquinolone adverse effects

A
  • photosensitivity
  • retinal degeneration - cats
  • cataracts
  • seizures
39
Q

bacitracin route and indication

A
  • topical

- feed additive (growth promotor)

40
Q

novobiocin treats

A
  • penicillin resistant staph
41
Q

virginiamycin effective against

A
  • toxoplasma gondii

- feed additive (growth promotor)

42
Q

sulphonamides should not be co-administered with

A
  • methenamine -> forms cyrstaluria
43
Q

growth promotor miscellaneous antimicrobials

A
  • bacitracin
  • carbadox
  • virginiamycin
44
Q

topical miscellaneous antimicrobials

A
  • bacitracin
  • thiostrepton
  • polymyxins
45
Q

toxicity of sulfonamides

A
  • keratoconjunctivitis
  • hepatic necrosis
  • nephrotoxicity
  • blood dyscrasias
46
Q

breed sensitivity of sulfonamides

A
  • doberman pinschers
  • hypoglycemia (dog and duck)
  • latrogenic hypothyroidism (dog)
47
Q

macrolides that treat mycoplasma

A
  • erythromycin (rhod equii & camp)
  • tilmicosin
  • tylosin
48
Q

not recommended in food producing animals

A
  • chloramphenicol
  • nitrofurans
  • vancomycin
  • metronidazole