Quiz 1 Flashcards
Bacterial Cell Wall Synthesis Drugs
- beta-lactams
- Bacitracin
- Vancomycin
- Cycloserine
Cell Membrane Drugs
- Polymyxin B
- Colistin
Protein Synthesis (30s) drugs
- Tetracycline
- Aminoglycoside
Protein Synthesis (50s) drugs
- Chloramphenicol
- Macrolides
- Lincosamides
Nucleic Acid Synthesis Drugs
- Fluorquninolones
- Metronidazole
- Rifampin
Folic Acid Synthesis Drugs
- Sulfonamides
- Diaminopyrimidines
Enteric Sulfonamides
- Succinylsulfathiazole
- Sulfasalazine
- Sulfaquinoxaline
- Sulfaguanidine
- Phthalylsulfathiazole
Topical Sulfonamides
- Silver sulfadiazine
- Mafenide
- Sulfacetamide
Ophthalmic Sulfonamides
- sulfacetamide
Diaminopyrimidines
- ormetoprim
- pyrimethamine
- trimethoprim
beta lactam antibiotics
- penicillin
- cephalosporin C
- carbapenems
- monobactams
Bacteriostatic Drugs
- tetracyclines
- chloramphenicol
- macrolides
- lincosamides
- sulfonamides
- diaminopyrimidines
Penicillinase-resistant penicillin (good oral)
- Oxacillin
- Cloxacillin
- Dicloxaxillin
Broad-spectrum penicillin
- amoxicillin
- ampicillin
extended spectrum/anti-pseudomonal penicillin
- ticarcillin
- carbenicillin
- piperacillin
- mezlocillin
- azlocillin
possess cephamycin group and effective against anaerobic microbes
- cefotetan
- cefoxitin
treats opthalamic and mastitis
- cefalonium
metabolized to desfuroylceftiofur
- cefitiofur
fourth generation cephalosporin
- cefepime
- cefquinome
common name for Convenia, long 1/2 life
- cefovecin
beta-lactamase inhibitor drugs
- cavulanic acid
- sulbactam
- tazobactam
Adverse effects of aminoglycosides
- nephrotoxicity
- ototoxicity (cats - vestibular; dogs - auditory)
- neuromuscular blockade
Natural tetracyclines
- chlortetracycline
- tetracycline
- oxytetracycline
semisynthetic tetracyclines
- doxycycline
- minocycline
adverse effects of tetracycline
- esophageal lesions - cats
- cardiac arrhythmias - horses
- alters commensal microflora - horses
- tooth mottling
- growth retardation
- hypersensitivity and drug fever - cats
Chloramphenicol derivatives
- thiamphenicol
- florfenicol
adverse effects of chloramphenicol
- does dependent bone marrow suppression
- aplastic anemia in humans
- gray baby syndrome
macrolide drugs
- erythromycin
- tilmicosin
- tylosin
- tulathromycin
- tiamulin
- azithromycin
- clarithromycin
macrolides oral absorption
- enteric coated oral formulation
macrolides that are Type III
- tulathromycin
- azithromycin
lincosamide drugs
- lincomycin
- clindamycin
lincomycin treats
- mycoplasma
clindamycin treats
- toxoplasma gondii
macrolides adverse effects
- oral administration contraindicated in hind gut fermentors
fluoroquinolones new generation
- premafloxacin
- pradofloxacin
fluroquinolone mechanism of action
- inhibits bacterial DNA gyrase/type II topoisomerase
fluroquinolone distribution
- bone
- prostate
- skin
- rapid accumulation in macrophages and neutrophils
fluroquinolone adverse effects
- photosensitivity
- retinal degeneration - cats
- cataracts
- seizures
bacitracin route and indication
- topical
- feed additive (growth promotor)
novobiocin treats
- penicillin resistant staph
virginiamycin effective against
- toxoplasma gondii
- feed additive (growth promotor)
sulphonamides should not be co-administered with
- methenamine -> forms cyrstaluria
growth promotor miscellaneous antimicrobials
- bacitracin
- carbadox
- virginiamycin
topical miscellaneous antimicrobials
- bacitracin
- thiostrepton
- polymyxins
toxicity of sulfonamides
- keratoconjunctivitis
- hepatic necrosis
- nephrotoxicity
- blood dyscrasias
breed sensitivity of sulfonamides
- doberman pinschers
- hypoglycemia (dog and duck)
- latrogenic hypothyroidism (dog)
macrolides that treat mycoplasma
- erythromycin (rhod equii & camp)
- tilmicosin
- tylosin
not recommended in food producing animals
- chloramphenicol
- nitrofurans
- vancomycin
- metronidazole
