P15 - GI Part 2 Flashcards
1
Q
cytoprotective drugs classes (4)
A
- antacids
- prostaglandin E1 analog
- sucralfate
- bismuth subsalicylate
2
Q
antacids MOA
A
- bases that react with HCL -> insoluble colloid & H2O
3
Q
non-systemic antacids drugs (2)
A
- aluminum hydroxide
- magnesium hydroxide
4
Q
systemic antacids drugs (1)
A
- sodium bicarbonate
5
Q
side effect of sodium bicarbonate
A
- bloat
6
Q
prostaglandin E1 analog MOA
A
- increase mucus & bicarb
- stabilizes mast cells
7
Q
prostaglandin E1 analog drugs
A
- misoprostol
8
Q
sucralfate MOA
A
- protect ulcer tissue from acid, bile and pepsin
9
Q
side effects of sucralfate
A
- decreases oral bioavability of other drugs
10
Q
sucralfate requires what type of environment
A
- acidic
11
Q
bismuth MOA
A
- absorbs E. coli entertoxins
12
Q
salicylate MOA
A
- decrease intestinal secretions
- anti-inflammatory
13
Q
salicylate is used cautiously in what species and why
A
- cats
- glucorconidation
14
Q
classes of drugs that increase GI motility (2)
A
- cholinergic agonists
- prokinetic agents
15
Q
cholinergic agonists MOA
A
- agonist on ACh receptors
- for GI muscle atony
16
Q
cholinergic agonists drugs (2)
A
- bethanechol
- carbachol