quiz 2 Flashcards
question: how does the am. cav. fold at day 20
- longitudinally
- lateral folds
- endo. becomes gut tube
- coelom in meso. becomes body cav.
- ecto. becomes skin - median plane
- makes the head and tail folds
- foregut and hindgut
- allantois = part of bladder
question: how does the am. cav. fold at day 25
- midgut gets defined
- oropharyngeal + cloacal mem. touching ectoderm
⤷ will eventually disintegrate to form opening for mouth and anus - yolk sac getting pinched + elongated
question: how does the am. cav. fold at day 30
- am. cav. reaches all the way around germ layers
⤷ ecto. folds around oropharyngeal + cloacal mem. - lateral folds become am. cav.
⤷ surrounds embryo
⤷ gut tube extends from oropharyngeal to cloacal mem. - evagination from gut tube becomes:
⤷ ant. pituitary
⤷ thyroid glands
⤷ lungs
⤷ liver
⤷ pancreas
⤷ brachial arches (pharynx, auditory tubes, tonsils, thymus, parathyroid glands) - coelom
⤷ fuses around heart -> pericardial cav.
⤷ expands -> pleural + peritoneal cav.
define: evagination
- outer pouch/pocket forming off side of organ
explain: limb bud development (date + location)
- upper = 24 days
- lower = 28 days
- limb tissues laid down in proximal to distal seq.
- apical ectodermal ridges form
define: apical ectodermal ridges
- thickening of ecto. (outer cells)
- stim. outward growth
question: what forms 1. skeleton 2. muscle 3. nervous sys.
- skeleton
- meso. or neural crest cells - muscle
- myoblasts: early emb. cells that become skeletal musc. fibers
⤷ derived from somites - nervous sys.
- neural tube
- neural crest cells
explain: thalidomide
- drug from 1950s prescribed to pregnant women for morning sickness
- led to developmental issues and miscarriages
⤷ caused no limbs and/or underdeveloped organ sys. - found to inhibit formation of blood vessel
⤷ apical dermal ridge has no blood supply -> stunts growth - once off drug, growth continued but skipped over a stage
⤷ continued growing from hands and feet
⤷ resulting in short/no limbs
define: blood islands and angioblasts
- blood islands: groups of angioblasts around meso.
⤷ on surface of yolk sac and inside embryo - angioblast: cell that diff. into endothelium of embryonic blood cells (blood vessels)
⤷ inside meso. = blood cells
⤷ outside meso. = blood vessels
explain: steps for heart development with dates
- day 20
⤷ 2 endocardial tubes form - day 21
⤷ endocardial tubes fuse together to form primitive heart tube - day 22
⤷ regions of heart tube start forming (4 dilations) - day 23 - 24 (bending of primitive heart)
⤷ heart bends to resemble the orientation of adult - day 28
⤷ atria and ventricles are in final adult position - day 46 - 50
⤷ blood flows through foramen ovale to bypass lungs
⤷ stays like this until birth
name: main dilations of primitive heart tube (4)
- sinus venosus
- atrium
- ventricle
- bulbus cordis
explain: changes in circulatory sys. of unborn fetus (compared to regular path)
- blood bypasses lungs
⤷ no O2 in lungs - blood bypasses liver
- placenta has oxygenated blood (no need lungs) and filters blood (no need liver)
question: how is blood carried to and from fetus (which structures)?
- O2 blood from placenta goes to fetus from umbilical vein
- O2 poor blood goes from fetus by umbilical arteries
explain: changes to circulatory sys. of newborn (from unborn fetus -> newborn)
- cut off supply from mat. O2 and nutrients
⤷ O2 lvls drop in child -> triggers breathing - air enters lungs -> blood flows into pulmonary artery
- blood passes lungs
⤷ begins “proper” movement of blood
question: what happens to fetal circulatory structures when born?
- foramen ovale closes
⤷ psi builds in L atria - ductus venosus, umb. vein and artery all degenerate
- ductus arteriosus closes
explain: pathway of blood in adult body
- deoxy. blood enters at inferior vena cava
- enters right atrium
- passes blood to right ventricle
- exits through pulmonary arteries to lungs
- pulmonary veins carry oxygenated blood back to heart
- enters left atrium
- passes blood to left ventricle
- exits through aorta to organs
explain: pathway of blood in unborn fetus
- oxy. + filtered blood from placenta bypasses liver through ductus venosus to vena cava (+ supplies some blood to liver)
- inferior vena cava directs mix of oxy. blood from placenta + deoxy. blood from body into right atrium
- passes blood through foramen ovale into left atrium (some goes through to right ventricle)
- blood bypasses lungs through ductus arteriosus and enters aorta
- supplies fetus body + supplies some blood to lungs
- blood enters umbilical arteries
- blood goes to placenta to be oxygenated
- umbilical veins carry oxy. blood to fetus back to ductus venosus
question: which struc. divert blood away from liver and lungs in fetal circ. sys.?
- ductus arteriosis and foramen ovale divert from lungs
- ductus venosus diverts from liver