Quiz 2 Flashcards
plasma membrane structure and function
structure: lipid bilayer
function: physical barrier, gateway for exchange, communication, and site of attachment
transcellular
transport that goes THROUGH the membrane
paracellular
transport that goes PARALLEL to the membrane
passive transport
materials move down gradient, no energy is required
active transport
materials move against gradient, requires energy (ATP)
What are the four types of passive flux?
simple diffusion
osmosis
facilitated diffusion
bulk filtration
simple diffusion
passive and random motion of molecules in solution
moving from high to low concentration
rapid over short distances
directly related to temp
indirectly related to molecular size and fluid viscocity
osmosis
diffusion of water across a selectively permeable membrane
high solute conc.= low H2O conc.
cells with high solute conc. have high osmotic pressures
isotonic solution
conc. of solute outside cell=conc inside the cell
hypertonic solution
conc. of solute outside cell>conc. inside the cell
water flows out (cell shrinks)
hypotonic solution
conc. of solute outside cell<conc. inside the cell
water flows in (cell swells)
aquaporins
membrane-transport proteins providing a facilitated pathway for water flow through the membrane
facilitated diffusion
“easier diffusion”
movement from high to low conc. through a protein
bulk filtration
concentrated movement of large groups of molecules (often including water)
everything moves in the same direction
often occurs in response to pressure
Fick’s law (equation)
Jnet=-Ds(dCs/dx)
- jnet= flu
- Ds= diffusion coefficient
- dCs/dx= concentration gradient of solute
Fick’s Law says…
flux is PROPORTIONAL to temp, concentration gradient, area, and membrane permeability
flux is INVERSELY proportional to friction, molecule size, fluid viscosity, and membrane thickness
Types of Transporters
ion channel
carriers
pumps
Ion channels
membrane proteins that, when open, act as a passive conduit for ions through the membrane
cycle between open and closed conformations
Ion channels gated by…
leaky
ligand
mechanical “pull”
voltage
some are sensitive to temp-how we detect hot/cold
leaky gated
channel randomly opens/closes