quiz 10 Flashcards
is rho gtpase involved in the SNARE hypothesis model mechanism?
no, rab gtpase is
T or F: adding a mannose phosphate to a protein that normally is constitutively secreted would make it accumulate in the ER
false
The plant cell organelle most analogous to animal cell lysosomes is the ______________
vacuole
T or F: Peroxisomes are not derived from the endoplasmic reticulum
true
In which organelle would you expect to first find a protein destined to be secreted from a cell?
endoplasmic reticulum
lysosomal storage diseases caused by a deficiency in lysosomal enzymes
-Hurler syndrome
-Hunter syndrome
-type II glycogenosis
-Tay-Sachs disease
the continuous release of mucus by the epithelial cells lining the respiratory tract is an example of ___________________
constitutive secretion
components of the core oligosaccharide side chain in the ER
-N-acetyl glucosamine
-mannose
-glucose
T or F: You have isolated two fractions containing similar-sized vesicles by centrifugation. You suspect one fraction contains lysosomes and the other contains peroxisomes. To confirm that a fraction contains peroxisomes, you would assay for acid phosphatase activity
false (catalase activity)
technique used to measure the strength of a v-SNARE-t-SNARE interaction
optical tweezers
Uptake of low-density lipoproteins (LDLs) occurs by _________________
receptor-mediated endocytosis
proteins that requires GTP in the process of LDL receptor-mediated endocytosis
dynamin