Quinolones Flashcards

1
Q

First generation

A

Naldixic acid

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2
Q

Second generation

A

pipemidic acid

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3
Q

Third generation

A

Ciprofloxacin ,ofloxacin ,levofloxacin

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4
Q

Fourth generation

A

Moxifloxacin ,trovafloxacin

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5
Q

Mechanism of action of Quinoline

A

Inhibit action of DNA Gyrase ,Topoisomerase 4

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6
Q

Quinolones are bactericidal

A

True

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7
Q

Spectrum of first and second Quinolones generation

A

Negative bacteria

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8
Q

Spectrum of Quinoline 3 RD generation

A

Gram positive, negative

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9
Q

Spectrum of fourth generation Quinolone

A

Against Gram positive, anaerobe

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10
Q

……. generation is used for systemic infection

A

3rd

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11
Q

…..,…. Are known as respiratory Quinolones

A

Levofloxacin , Moxifloxacin

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12
Q

Atypical respiratory pathogens

A

Leĝionella ,mycoplasma

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13
Q

Co trimoxazole is mix between….,…..

A

Sulfamethoxazole ,trimethoprim

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14
Q

Spectrum of sulfonamide ,trimethoprim

A

Gram positive ,some gram negative

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15
Q

Salmonella in fection treated by

A

Co trimoxazole

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16
Q

Steven johnson syndrome is amanifestation.of ……

A

Co trimoxazole

17
Q

Kernicterus is aside effect of co trimoxazole

A
18
Q

Renal tube defect is caused by ……

A

Co trimoxazole

19
Q

Spectrum of metronidazole

A

Anti protozoal agent+ anaerobic bacteria

20
Q

Dark brown urine is caused by ……

A

Metronidazole

21
Q

Di sulfiram like reaction is caused by ….

A

Metronidazole

22
Q

What is the uses of metronidazole

A

Anaerobic infection
Pseudomembranous colitis
Acute ulcerstive gingivitis

23
Q

The most common side effect of Quinoline is

A

GIT upset

24
Q

The most common side effect of Quinoline is

A

GIT upset

25
Q

ما هي ثأثير ال ciprofloxacin علي الحوامل والكبار

A

Tendinitis,arthropathy

26
Q

ما هي ثأثير ال ciprofloxacin علي الحوامل والكبار

A

Tendinitis,arthropathy

27
Q

Quinomones بتعمل seizers

A

T

28
Q

Quinomones بتعمل seizers

A

T

29
Q

ماهي الادويه التي يؤثر عليها الوQuinomone

A

Theophylline, warfarin, sulfonylureas

30
Q

Respiratory infection treated by

A

Co trimoxazole

31
Q

Respiratory infection treated by

A

Co trimoxazole

32
Q

Sialodenitis is treated

A

Cotrimoxazole