Quinolones Flashcards by Mohamed Shabka

Q

First generation

A

Naldixic acid

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Q

Second generation

A

pipemidic acid

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Q

Third generation

A

Ciprofloxacin ,ofloxacin ,levofloxacin

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Q

Fourth generation

A

Moxifloxacin ,trovafloxacin

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Q

Mechanism of action of Quinoline

A

Inhibit action of DNA Gyrase ,Topoisomerase 4

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Q

Quinolones are bactericidal

A

True

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Q

Spectrum of first and second Quinolones generation

A

Negative bacteria

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Q

Spectrum of Quinoline 3 RD generation

A

Gram positive, negative

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Q

Spectrum of fourth generation Quinolone

A

Against Gram positive, anaerobe

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Q

……. generation is used for systemic infection

A

3rd

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Q

…..,…. Are known as respiratory Quinolones

A

Levofloxacin , Moxifloxacin

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Q

Atypical respiratory pathogens

A

Leĝionella ,mycoplasma

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Q

Co trimoxazole is mix between….,…..

A

Sulfamethoxazole ,trimethoprim

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Q

Spectrum of sulfonamide ,trimethoprim

A

Gram positive ,some gram negative

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Q

Salmonella in fection treated by

A

Co trimoxazole

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Q

Steven johnson syndrome is amanifestation.of ……

A

Co trimoxazole

Q

Kernicterus is aside effect of co trimoxazole

A

Q

Renal tube defect is caused by ……

A

Co trimoxazole

Q

Spectrum of metronidazole

A

Anti protozoal agent+ anaerobic bacteria

Q

Dark brown urine is caused by ……

A

Metronidazole

Q

Di sulfiram like reaction is caused by ….

A

Metronidazole

Q

What is the uses of metronidazole

A

Anaerobic infection
Pseudomembranous colitis
Acute ulcerstive gingivitis

Q

The most common side effect of Quinoline is

A

GIT upset

Q

The most common side effect of Quinoline is

A

GIT upset

Q

ما هي ثأثير ال ciprofloxacin علي الحوامل والكبار

A

Tendinitis,arthropathy

Q

ما هي ثأثير ال ciprofloxacin علي الحوامل والكبار

A

Tendinitis,arthropathy

Q

Quinomones بتعمل seizers

A

T

Q

Quinomones بتعمل seizers

A

T

Q

ماهي الادويه التي يؤثر عليها الوQuinomone

A

Theophylline, warfarin, sulfonylureas

Q

Respiratory infection treated by

A

Co trimoxazole

Q

Respiratory infection treated by

A

Co trimoxazole

Q

Sialodenitis is treated

A

Cotrimoxazole