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Pharma > Oral Antidiabetics > Flashcards

Oral Antidiabetics Flashcards

1
Q

Sulfonylureas members

A

Glibenclamide
Gliclazide
Glipizide

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2
Q

Sulfonylureas mechanism

A

Increase insulin secretion by pancreatic Beta cells

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3
Q

What is the adverse effects of sulfonylureas

A

Hypoglycemia
الناس اللي عندها مشاكل ف الكبد أو الكليه ،كبار السن ،ولفتره طويله
Weight gain
Hepatotoxicity

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4
Q

What is the adverse effects of sulfonylureas

A

Hypoglycemia
الناس اللي عندها مشاكل ف الكبد أو الكليه ،كبار السن ،ولفتره طويله
Weight gain
Hepatotoxicity

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5
Q

Biguanides example

A

Metformin

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6
Q

Biguanides mechsnism

A

بتقلل الجلوكوز
الامتصاص من الأمعاء والتكوين
وبتزود حساسية المستقبلات

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7
Q

Biguanides mechsnism

A

بتقلل الجلوكوز
الامتصاص من الأمعاء والتكوين
وبتزود حساسية المستقبلات

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8
Q

T,F
Biguanides cuase hypoglycemia,increase secretion

A

No

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9
Q

Biguanides استخدامات

A

النزع التاني
الناس التخينه

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10
Q

الاثار الجانبيه لل biguanides

A

مشاكل ف ال GIT
نقص امتصاص
Lactic acidosis مع بتوع الكحل

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11
Q

الاثار الجانبيه لل biguanides

A

مشاكل ف ال GIT
نقص امتصاص
Lactic acidosis مع بتوع الكحل

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12
Q

Thiazolidinediones example

A

Pioglitazone
Rosiglitazone

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13
Q

Thiazolidinediones mechanism

A

حساسيه
عدد
جينات

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14
Q

استخدامات ال thiazolidinediones

A

Type 20 insulin resistance

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15
Q

اثار ال thiazolidinediones

A

تسمم الكبد
احتقان السوائل متفعشي مع عيان CHF

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